Downtown San Francisco accommodation with spa

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Downtown San Francisco

17 May - 18 May
Tonight
Check prices in Downtown San Francisco for tonight, 17 May - 18 May
18 May - 19 May
Tomorrow night
Check prices in Downtown San Francisco for tomorrow night, 18 May - 19 May

Featured Downtown San Francisco Spa Hotels

The Huntington Hotel
Great for spa weekends

The Huntington Hotel

5 out of 5
1075 California St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is AU$1,378 per night from 13 June to 14 June
AU$1,378
13 June - 14 June
includes taxes & fees
In the heart of San Francisco, The Huntington Hotel is within a 5-minute drive of Moscone Convention Center and Oracle Park.
Opens in a new window The Huntington Hotel
Hotel Nikko San Francisco
Great for spa weekends

Hotel Nikko San Francisco

4.5 out of 5
222 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is AU$385 per night from 25 May to 26 May
AU$385
25 May - 26 May
includes taxes & fees
With a stay at Hotel Nikko San Francisco, you'll be centrally located in San Francisco, just a 3-minute walk from Union Square and 11 minutes by foot from Moscone ...
Opens in a new windowHotel Nikko San Francisco
InterContinental San Francisco by IHG
Great for spa weekends

InterContinental San Francisco by IHG

4 out of 5
888 Howard Street San Francisco CA
Fully refundable
The price is AU$372 per night from 29 May to 30 May
AU$372
29 May - 30 May
includes taxes & fees
InterContinental San Francisco by IHG is centrally located in San Francisco, a 5-minute walk from Moscone Convention Center and 6 minutes by foot from Yerba ...
Opens in a new windowInterContinental San Francisco by IHG
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

5 out of 5
2 New Montgomery St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is AU$538 per night from 28 May to 29 May
AU$538
28 May - 29 May
includes taxes & fees
With a stay at Palace Hotel, a Luxury Collection Hotel, San Francisco, you'll be centrally located in San Francisco, just a 4-minute walk from San Francisco ...
Opens in a new windowPalace Hotel, a Luxury Collection Hotel, San Francisco
The Donatello

The Donatello

3.5 out of 5
501 Post St San Francisco CA
With a stay at The Donatello, you'll be centrally located in San Francisco, steps from Union Square and 15 minutes by foot from Moscone Convention Center.
Get rates
Opens in a new windowThe Donatello
W San Francisco

W San Francisco

4.5 out of 5
181 3rd St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is AU$342 per night from 5 June to 6 June
AU$342
5 June - 6 June
includes taxes & fees
With a stay at W San Francisco, you'll be centrally located in San Francisco, steps from Moscone Convention Center and San Francisco Museum of Modern Art.
Opens in a new windowW San Francisco
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
The price is AU$290 per night from 7 June to 8 June
AU$290
7 June - 8 June
includes taxes & fees
A stay at Hilton San Francisco Union Square places you in the heart of San Francisco, within a 5-minute drive of Westfield San Francisco Centre and Ferry ...
Opens in a new windowHilton San Francisco Union Square
Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero

5 out of 5
222 Sansome St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is AU$735 per night from 5 June to 6 June
AU$735
5 June - 6 June
includes taxes & fees
A stay at Four Seasons Hotel San Francisco at Embarcadero places you in the heart of San Francisco, within a 15-minute walk of Moscone Convention Center and ...
Opens in a new windowFour Seasons Hotel San Francisco at Embarcadero
Four Seasons Hotel San Francisco
Great for spa weekends

Four Seasons Hotel San Francisco

5 out of 5
757 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is AU$848 per night from 25 May to 26 May
AU$848
25 May - 26 May
includes taxes & fees
A stay at Four Seasons Hotel San Francisco places you in the heart of San Francisco, within a 5-minute drive of Moscone Convention Center and Ferry ...
Opens in a new windowFour Seasons Hotel San Francisco
Don't see what you're looking for?
See all available properties in Downtown San Francisco
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Downtown San Francisco hotels essential information

Accommodation
835 hotels
Lowest Price
AU$290
Highest Price
AU$1,378
Popular hotels
 The Huntington Hotel, Hotel Nikko San Francisco, InterContinental San Francisco by IHG, Palace Hotel, a Luxury Collection Hotel, San Francisco, The Donatello, W San Francisco, Hilton San Francisco Union Square, Four Seasons Hotel San Francisco at Embarcadero, Four Seasons Hotel San Francisco

Most recent Downtown San Francisco hotel reviews

Holiday Inn Golden Gateway by IHG
lastminute.com.au Verified Review
5 / 5
My room was clean and comfortable, and the hotel in general was well kept up. I have no complaints--and the price was more than reasonable.
A verified traveller stayed at Holiday Inn Golden Gateway by IHG
Posted 2 hours ago
Holiday Inn Golden Gateway by IHG

More ways to explore Downtown San Francisco

Top Picks