Find Uptown hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Uptown

Top trending hotels in Uptown

La Quinta Inn & Suites by Wyndham San Antonio Airport

La Quinta Inn & Suites by Wyndham San Antonio Airport

3 out of 5
850 Halm Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
With a stay at La Quinta Inn & Suites by Wyndham San Antonio Airport in San Antonio (Uptown), you'll be a 2-minute drive from North Star Mall and 6 minutes from ...
La Quinta Inn & Suites by Wyndham San Antonio Airport
Crowne Plaza San Antonio Airport by IHG

Crowne Plaza San Antonio Airport by IHG

3.5 out of 5
1111 NE Loop 410, San Antonio, TX
Fully refundable
With a stay at Crowne Plaza San Antonio Airport by IHG in San Antonio (Uptown), you'll be a 3-minute drive from North Star Mall and 7 minutes from San Antonio ...
Crowne Plaza San Antonio Airport by IHG
Spark by Hilton San Antonio Airport

Spark by Hilton San Antonio Airport

2 out of 5
8640 Crownhill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
With a stay at Spark by Hilton San Antonio Airport in San Antonio (Uptown), you'll be a 4-minute drive from North Star Mall and 8 minutes from San Antonio Zoo ...
Spark by Hilton San Antonio Airport
Save an average of 15% on thousands of hotels when you're signed in
Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport

3 out of 5
95 NE Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
With a stay at Drury Plaza Hotel San Antonio Airport in San Antonio (Uptown), you'll be a 1-minute drive from North Star Mall and 6 minutes from San Antonio ...
Drury Plaza Hotel San Antonio Airport
Hampton Inn & Suites San Antonio-Airport

Hampton Inn & Suites San Antonio-Airport

2.5 out of 5
8902 Jones Maltsberger Rd, San Antonio, TX
Fully refundableReserve now, pay when you stay
With a stay at Hampton Inn & Suites San Antonio-Airport in San Antonio (Uptown), you'll be a 2-minute drive from North Star Mall and 6 minutes from San Antonio ...
Hampton Inn & Suites San Antonio-Airport
Red Roof Inn San Antonio - Airport

Red Roof Inn San Antonio - Airport

2 out of 5
333 Wolfe Road, San Antonio, TX
Fully refundableReserve now, pay when you stay
With a stay at Red Roof Inn San Antonio - Airport in San Antonio (Uptown), you'll be a 3-minute drive from North Star Mall and 6 minutes from San Antonio Zoo ...
Red Roof Inn San Antonio - Airport
Estancia del Norte San Antonio, Tapestry Collection by Hilton

Estancia del Norte San Antonio, Tapestry Collection by Hilton

3.5 out of 5
37 Ne Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
With a stay at Estancia del Norte San Antonio, Tapestry Collection by Hilton in San Antonio (Uptown), you'll be a 1-minute drive from North Star Mall and 6 minutes ...
Estancia del Norte San Antonio, Tapestry Collection by Hilton
Pear Tree Inn San Antonio Airport

Pear Tree Inn San Antonio Airport

2.5 out of 5
143 NE Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
With a stay at Pear Tree Inn San Antonio Airport in San Antonio (Uptown), you'll be a 2-minute drive from North Star Mall and 6 minutes from San Antonio Zoo ...
Pear Tree Inn San Antonio Airport
Courtyard by Marriott San Antonio Airport

Courtyard by Marriott San Antonio Airport

3 out of 5
8615 Broadway St, San Antonio, TX
Fully refundableReserve now, pay when you stay
Located in San Antonio (Uptown), Courtyard by Marriott San Antonio Airport is within a 15-minute drive of San Antonio Zoo and Aquarium and Alamo.
Courtyard by Marriott San Antonio Airport
Don't see what you're looking for?
See all available properties in Uptown
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Uptown Hotels

Haven’t you been dying to check out that swanky new coffee shop? What about the recently opened bar serving drinks in mason jars? And let’s not forget about the barber shops willing to give you a shaved-on-the-sides, long-on-top cut whenever you want. Don’t worry; we’ll help you find the best deals at hotels in Uptown.

This hip new ’hood will charm the-you-know-what off you. Uptown hotels are comfortable and affordable, and many offer amenities like room service for those late-night meals, as well as a pool to swim in. Some of these hotels will also have you near great shopping such as souvenir shops, clothing boutiques and everything in between. Don’t feel like leaving the hotel for dinner and drinks? Hang out in the lobby bar and meet some of your fellow travellers—you never what kinds of stories they have in their memory log.

There’s no point in going somewhere if you’re not going to stay where all the action is. lastminute.com.au gets you the best offers on where to stay in Uptown so you don’t have to waste endless hours searching online. The trip of a lifetime is at your fingertips. Click and go!

Uptown hotels essential information

Accommodation
5,646 hotels
Lowest Price
Highest Price
Popular hotels
La Quinta Inn & Suites by Wyndham San Antonio Airport, Crowne Plaza San Antonio Airport by IHG, Spark by Hilton San Antonio Airport, Drury Plaza Hotel San Antonio Airport, Hampton Inn & Suites San Antonio-Airport, Red Roof Inn San Antonio - Airport, Estancia del Norte San Antonio, Tapestry Collection by Hilton, Pear Tree Inn San Antonio Airport, Courtyard by Marriott San Antonio Airport

Most recent Uptown hotel reviews