Find Midtown hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Midtown

Top trending hotels in Midtown

Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is AU$230 per night from 5 Apr to 6 Apr
AU$230
5 Apr - 6 Apr
includes taxes & fees
Located in St. Louis (Midtown), Element St. Louis Midtown is within a 5-minute drive of St. Louis University and St. Louis Union Station.
Opens in a new windowElement St. Louis Midtown
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is AU$204 per night from 5 Apr to 6 Apr
AU$204
5 Apr - 6 Apr
includes taxes & fees
With a stay at Residence Inn by Marriott St Louis Downtown, you'll be centrally located in St. Louis, within a 5-minute drive of St. Louis Union Station and ...
Opens in a new windowResidence Inn by Marriott St Louis Downtown
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is AU$192 per night from 5 Apr to 6 Apr
AU$192
5 Apr - 6 Apr
includes taxes & fees
A stay at Pear Tree Inn St. Louis Near Union Station places you in the heart of St. Louis, within a 15-minute walk of St. Louis Union Station and Enterprise ...
Opens in a new windowPear Tree Inn St. Louis Near Union Station
Save an average of 15% on thousands of hotels when you're signed in
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is AU$249 per night from 5 Apr to 6 Apr
AU$249
5 Apr - 6 Apr
includes taxes & fees
With a stay at Drury Inn & Suites St. Louis Union Station, you'll be centrally located in St. Louis, just a 5-minute walk from St. Louis Union Station and 11 ...
Opens in a new windowDrury Inn & Suites St. Louis Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is AU$235 per night from 5 Apr to 6 Apr
AU$235
5 Apr - 6 Apr
includes taxes & fees
A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of Enterprise Center and St. Louis Union Station.
Opens in a new window21C Museum Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is AU$276 per night from 5 Apr to 6 Apr
AU$276
5 Apr - 6 Apr
includes taxes & fees
A stay at Drury Plaza Hotel St. Louis at the Arch places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Busch Stadium.
Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is AU$290 per night from 12 Apr to 13 Apr
AU$290
12 Apr - 13 Apr
includes taxes & fees
A stay at Hyatt Regency St. Louis at The Arch places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Busch Stadium.
Opens in a new windowHyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is AU$169 per night from 12 Apr to 13 Apr
AU$169
12 Apr - 13 Apr
includes taxes & fees
With a stay at Clayton Plaza Hotel & Extended Stay in St. Louis (Clayton), you'll be within a 5-minute drive of Forest Park and Washington University in St. ...
Opens in a new windowClayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
The price is AU$208 per night from 6 Apr to 7 Apr
AU$208
6 Apr - 7 Apr
includes taxes & fees
Located in Maryland Heights, Hollywood Casino & Hotel St. Louis is on a river, just a 3-minute walk from Hollywood Casino and a 4-minute drive from Hollywood ...
Opens in a new windowHollywood Casino & Hotel St. Louis
Don't see what you're looking for?
See all available properties in Midtown
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Midtown Hotels

Haven’t you been dying to check out that swanky new coffee shop? What about the recently opened bar serving drinks in mason jars? And let’s not forget about the barber shops willing to give you a shaved-on-the-sides, long-on-top cut whenever you want. Don’t worry; we’ll help you find the best deals at hotels in Midtown.

This hip new ’hood will charm the-you-know-what off you. Midtown hotels are comfortable and affordable, and many offer amenities like room service for those late-night meals, as well as a pool to swim in. Some of these hotels will also have you near great shopping such as souvenir shops, clothing boutiques and everything in between. Don’t feel like leaving the hotel for dinner and drinks? Hang out in the lobby bar and meet some of your fellow travellers—you never what kinds of stories they have in their memory log.

There’s no point in going somewhere if you’re not going to stay where all the action is. lastminute.com.au gets you the best offers on where to stay in Midtown so you don’t have to waste endless hours searching online. The trip of a lifetime is at your fingertips. Click and go!

Midtown hotels essential information

Accommodation
1,896 hotels
Lowest Price
AU$169
Highest Price
AU$290
Popular hotels
Element St. Louis Midtown, Residence Inn by Marriott St Louis Downtown, Drury Plaza Hotel St. Louis at the Arch, Pear Tree Inn St. Louis Near Union Station, Clayton Plaza Hotel & Extended Stay, 21C Museum Hotel St Louis , Hyatt Regency St. Louis at The Arch, Hollywood Casino & Hotel St. Louis, Drury Inn & Suites St. Louis Union Station

Most recent Midtown hotel reviews

Top Picks