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21C Museum Hotel St Louis

4.5 star property

Photo gallery for 21C Museum Hotel St Louis

Exterior
Billiards
Indoor pool
Interior
Bar (on property)

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

View map
1528 Locust street, St. Louis, MO, 63103
  • St. Louis Union Station
    ‪6 min walk‬
  • Enterprise Center
    ‪6 min walk‬
  • Busch Stadium
    ‪14 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

Room options

Loft, 2 Queen Beds

  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

  • 51 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed)

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

  • 25 sq m
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

  • 104 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(68 reviews)
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Double Room, 2 Queen Beds

8.6 out of 10
Excellent
(19 reviews)
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

8.8 out of 10
Excellent
(23 reviews)
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed

  • 48 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 King Bed

9.2 out of 10
Wonderful
(5 reviews)
  • 48 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

9.0 out of 10
Wonderful
(20 reviews)
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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Hyatt Regency St. Louis at The Arch

  • Pet-friendly
  • Free WiFi
  • Restaurant
  • Air conditioning
4.2 out of 5, Very good, (3961)
The price is AU$316
for 1 room
includes taxes & fees
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About the area

St. Louis

A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of City Museum and Enterprise Center. .This luxury hotel is 0.6 mi (1 km) from St. Louis Union Station and 0.7 mi (1.1 km) from America's Center Convention Complex.

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • Busch Stadium - 14 min walk - 1.2 km
  • Gateway Arch - 2 min drive - 1.8 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with a fitness center and a steam room
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
Make yourself at home in one of the 104 air-conditioned rooms featuring espresso makers and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include phones, as well as safes and desks.
Don't miss out on the many recreational opportunities, including an indoor pool, a steam room, and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and a banquet hall.
Enjoy a meal at the restaurant or snacks in the coffee shop/cafe. The hotel also offers room service (during limited hours). Wrap up your day with a drink at the bar/lounge. Cooked-to-order breakfasts are available daily from 6:30 AM to 1:00 PM for a fee.
Featured amenities include a business center, dry cleaning/laundry services, and a 24-hour front desk.
Cooked-to-order breakfasts are available for a surcharge and are served each morning between 6:30 AM and 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Languages

English

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 935 out of 1295 reviews
Rating 8 - Good. 192 out of 1295 reviews
Rating 6 - Okay. 77 out of 1295 reviews
Rating 4 - Poor. 41 out of 1295 reviews
Rating 2 - Terrible. 50 out of 1295 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

8/10 Good

Kyle

Travelled with family
Liked: Cleanliness, staff & service, room comfort

Some good, some not so good...

Great hotel, but needs some TLC. It was not super clean -- the elevators got stuck -- and the AC made a strange noise whenever it kicked in. On the other hand -- the staff was incredibly kind and responsive and the bar was alot of fun. I will go back!
Stayed 4 nights in May 2025

10/10 Excellent

Travon

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

A Gem

Very well appointed, spacious room with modern lighting and climate controls. Pleasant, attentive staff. Highly recommend :)
Stayed 4 nights in May 2025

10/10 Excellent

Deanna

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

An amazing hotel

This hotel is beautiful and unique. It has the best fitness center I have ever seen in a hotel and the best pool. The pool is Olympic sized. The rooms were quiet and comfortable. The museum of pop art fun to visit.
The pool
View from the room
Art gallery at the hotel that used to be a full size basketball court
Stayed 3 nights in May 2025

10/10 Excellent

Cristina

Travelled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely historic hotel. Amenities - pool and fitness center were excellent. Walkable to the City Museum. Would definitely stay here again.
Stayed 1 night in May 2025

10/10 Excellent

michelle

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great place and cool decor.

Service was great and the hotel/museum is beautiful.
Stayed 1 night in May 2025

10/10 Excellent

Erin

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in May 2025

8/10 Good

Lynn, St. Louis

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is a very unique and interesting hotel. The art is beautiful as is the whole hotel. We had a corner king and it was plenty of room for 2. The furnishings were artsy and fun. Only complaint was that the pillows weee way too dense and BIG. Not very comfortable for our liking. The bed and sheets were lovely. Other than that we loved our stay. Thank you.
Stayed 1 night in May 2025

10/10 Excellent

Derek

Stayed 1 night in Apr 2025

10/10 Excellent

Margaret

Stayed 1 night in Apr 2025

10/10 Excellent

John

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great gym and pool, fun atmosphere on main level
Stayed 1 night in Apr 2025

8/10 Good

Jerome

Travelled with group
Liked: Cleanliness, property conditions & facilities, room comfort
Stayed 1 night in May 2025

4/10 Poor

John

Travelled with family and small children
Disliked: Staff & service, amenities, property conditions & facilities
I've stayed at 21c in Nashville and fully enjoyed the experience. In St. Louis it's not in a great neighborhood, very run down. The room phone never worked thank got for cell phones and elevators. The temperature controls didn't work properly. Fire alarm went off in the middle of the day while my 3 year old grandson was sleeping my daughter in law had to carry him down ten flights of stairs only to be told it was a mistake alarm. Valet parking is $50 for an open fenced lot across the street??? We walked around one afternoon and never really found anything cool or fun to go do... I would avoid this hotel get something g. Lose to the. Cardinals ball park same pricing with a way better experience!
Stayed 3 nights in Apr 2025

6/10 Okay

Jessica

Travelled with partner
Liked: Cleanliness, amenities
Disliked: Staff & service
Looks good and the toiletries brand is amazing
Stayed 1 night in Apr 2025

10/10 Excellent

Richard, Hickory

Stayed 1 night in Apr 2025

10/10 Excellent

Moe

Stayed 3 nights in Apr 2025

10/10 Excellent

Joni

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Spectacular restaurant, comfortable room, good museum, and it feels safe. The elevator has keyed access to each floor.
Stayed 2 nights in Apr 2025

8/10 Good

Fran

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Repeat Customer

This was our 2nd stay which speaks volumes! We love this place. It is upscale but relaxed. Historic but modern. Great location in walking distance of many attractions, but quiet. Clean. So Clean. I feel very comfortable walking around the room without shoes. Just a couple issues I will note...no after hours room service or even vending to get a snack or drink. And, only 1 roll of toilet paper. I think 2 rolls would have made us less nervous.😉
Stayed 1 night in Apr 2025

6/10 Okay

Siegfried

Liked: Cleanliness, amenities, property conditions & facilities
Bar service was very slow. Staff didn’t tell us there was a coffee shop.
Stayed 2 nights in Apr 2025

8/10 Good

Heather

Liked: Cleanliness, property conditions & facilities
This hotel has a lot of potential. It’s in a good area of the city. The hotel itself is so fun bright colored wallpaper art all over the place pool hot tub saunas pool tables literally has something for everybody. The front desk staff was OK. The valet attendant were fantastic all in all enjoyed the trip
Stayed 2 nights in Apr 2025

10/10 Excellent

Elia

Liked: Cleanliness, staff & service, property conditions & facilities
Me gusto mucho la atencion al cliente y el progecionalizmo. Gracias
Stayed 2 nights in Apr 2025

10/10 Excellent

Sandra

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We enjoyed our two nights at this hotel. The property was nice and we were able to walk to Enterprise stadium easily.
Stayed 2 nights in Apr 2025

10/10 Excellent

Hilary

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Loved everything! Will be back!

We will be coming back! We absolutely loved the hotel. From the rooms (we had a Deluxe King Suite) to the restaurants to the huge art museum…it did not disappoint. It was also within walking distance to our event at Enterprise Center. Staff were very friendly. Although we didn’t get in, the pool and hot tub both were large and looked nice. They also have two huge weight/workout rooms, treatment rooms, steam rooms, etc.
Stayed 1 night in Apr 2025

8/10 Good

Kenda

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

10/10 Excellent

Andrea, Du Quoin Illinois

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I stayed at this hotel for the stl go marathon and absolutely loved it! Super close to the start/finish so that was convenient. The hotel itself was beautiful and unique. From the art, to the amenities, and staff! Ugh it was all perfect. I will be staying here again next time I’m in town. 10/10!
One of the art galleries
View from the hotel window
Stayed 1 night in Apr 2025