Book Holiday Homes in Illinois Medical District Station

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in Illinois Medical District Station

Newly Updated Vintage 6 Bedroom Single Family Home by AllSet Turnover

Newly Updated Vintage 6 Bedroom Single Family Home by AllSet Turnover

825 S Claremont, Chicago, IL
With a stay at this vacation home in Chicago (Near West Side), you'll be within a 5-minute drive of United Center and University of Illinois Chicago.
Get rates
Newly Updated Vintage 6 Bedroom Single Family Home by AllSet Turnover
Remodeled 1890 Chicago Greystone, 4bd 3.5ba & Gym

Remodeled 1890 Chicago Greystone, 4bd 3.5ba & Gym

Chicago
With a stay at this vacation home in Chicago (Near West Side), you'll be within a 5-minute drive of United Center and University of Illinois Chicago.
Get rates
Remodeled 1890 Chicago Greystone, 4bd 3.5ba & Gym
Chicago West Town Row House

Chicago West Town Row House

2 out of 5
Chicago
With a stay at this vacation home in Chicago (West Town), you'll be within a 5-minute drive of United Center and Chicago Riverwalk.
Get rates
Chicago West Town Row House
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Beautiful Modern Designer Home ~ Downtown - 4-Bed/4-Bath

Beautiful Modern Designer Home ~ Downtown - 4-Bed/4-Bath

Chicago
With a stay at this vacation home, you'll be centrally located in Chicago, within a 5-minute drive of United Center and Michigan Avenue.
Get rates
Beautiful Modern Designer Home ~ Downtown - 4-Bed/4-Bath
Private Historic Coach House Wicker Park

Private Historic Coach House Wicker Park

Chicago
With a stay at this vacation home, you'll be centrally located in Chicago, within a 5-minute drive of United Center and Michigan Avenue.
Get rates
Private Historic Coach House Wicker Park
Charming 3-bedroom house in awesome Chicago with AC, WiFi

Charming 3-bedroom house in awesome Chicago with AC, WiFi

Chicago
With a stay at this vacation home in Chicago (West Town), you'll be within a 5-minute drive of United Center and University of Illinois Chicago.
Get rates
Charming 3-bedroom house in awesome Chicago with AC, WiFi
HUGE 1700 sqft 3bd West Loop Penthouse w/ Balcony

HUGE 1700 sqft 3bd West Loop Penthouse w/ Balcony

Chicago
With a stay at this vacation home, you'll be centrally located in Chicago, within a 5-minute drive of United Center and Michigan Avenue.
Get rates
HUGE 1700 sqft 3bd West Loop Penthouse w/ Balcony
Beautiful Designer Townhome ~ Amazing Location! River West - 4-Bedroom / Unit 1

Beautiful Designer Townhome ~ Amazing Location! River West - 4-Bedroom / Unit 1

Chicago
With a stay at this vacation home, you'll be centrally located in Chicago, within a 5-minute drive of United Center and Michigan Avenue.
Get rates
Beautiful Designer Townhome ~ Amazing Location! River West - 4-Bedroom / Unit 1
Luxury Modern home minutes from Downtown Chicago

Luxury Modern home minutes from Downtown Chicago

Chicago
With a stay at this vacation home in Chicago (Lower West Side), you'll be within a 5-minute drive of McCormick Place and United Center.
Get rates
Luxury Modern home minutes from Downtown Chicago
Don't see what you're looking for?
See all available properties in Illinois Medical District Station
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top trending hotels in Illinois Medical District Station

Congress Plaza Hotel

Congress Plaza Hotel

3.5 out of 5
520 South Michigan Avenue, Chicago, IL
The price is AU$229 per night from 11 May to 12 May
AU$229
includes taxes & fees
11 May - 12 May
With a stay at Congress Plaza Hotel, you'll be centrally located in Chicago, steps from Columbia College Chicago and Museum of Contemporary Photography.
Congress Plaza Hotel
Hilton Chicago/Magnificent Mile Suites

Hilton Chicago/Magnificent Mile Suites

3.5 out of 5
198 E Delaware Pl, Chicago, IL
The price is AU$276 per night from 11 May to 12 May
AU$276
includes taxes & fees
11 May - 12 May
With a stay at Hilton Chicago/Magnificent Mile Suites, you'll be centrally located in Chicago, steps from Michigan Avenue and 8 minutes by foot from Lake ...
Hilton Chicago/Magnificent Mile Suites
Embassy Suites by Hilton Chicago Downtown River North

Embassy Suites by Hilton Chicago Downtown River North

4 out of 5
600 N State St, Chicago, IL
The price is AU$314 per night from 26 May to 27 May
AU$314
includes taxes & fees
26 May - 27 May
With a stay at Embassy Suites by Hilton Chicago Downtown River North, you'll be centrally located in Chicago, just a 4-minute walk from Michigan Avenue and 9 ...
Embassy Suites by Hilton Chicago Downtown River North
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
The Westin Michigan Avenue Chicago

The Westin Michigan Avenue Chicago

4.5 out of 5
909 North Michigan Ave, Chicago, IL
The price is AU$324 per night from 26 May to 27 May
AU$324
includes taxes & fees
26 May - 27 May
With a stay at The Westin Michigan Avenue Chicago, you'll be centrally located in Chicago, steps from Michigan Avenue and 6 minutes by foot from Lake ...
The Westin Michigan Avenue Chicago
Don't see what you're looking for?
See all available properties in Illinois Medical District Station
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.