Book Upstate South Carolina hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Upstate South Carolina

Cheap Upstate South Carolina hotels

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Fully refundable
The price is AU$156 per night from 14 June to 15 June
AU$156
14 June - 15 June
includes taxes & fees
When you stay at Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG in Greenville, you'll be in a shopping district, a 3-minute drive from Haywood Mall ...
Opens in a new windowCrowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
The price is AU$180 per night from 24 May to 25 May
AU$180
24 May - 25 May
includes taxes & fees
With a stay at Embassy Suites Greenville Golf Resort & Conference Center in Greenville, you'll be within a 10-minute drive of Haywood Mall and The Shops at ...
Opens in a new windowEmbassy Suites Greenville Golf Resort & Conference Center
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is AU$545 per night from 7 June to 8 June
AU$545
7 June - 8 June
includes taxes & fees
With a stay at Grand Bohemian Lodge Greenville, Autograph Collection in Greenville (Greenville Downtown), you'll be within a 10-minute drive of Haywood Mall ...
Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Save an average of 15% on thousands of hotels when you're signed in
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
The price is AU$161 per night from 31 May to 1 June
AU$161
31 May - 1 June
includes taxes & fees
Located in Greenville, Hilton Greenville is in the business district, a 2-minute drive from Haywood Mall and 6 minutes from Bon Secours Wellness Arena.
Opens in a new windowHilton Greenville
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
The price is AU$303 per night from 1 June to 2 June
AU$303
1 June - 2 June
includes taxes & fees
Located in Greenville, Hotel Hartness is in the suburbs, within a 15-minute drive of Haywood Mall and BMW Performance Center.
Opens in a new windowHotel Hartness
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
The price is AU$127 per night from 31 May to 1 June
AU$127
31 May - 1 June
includes taxes & fees
With a stay at Best Western Plus Greenville I-385 Inn & Suites, you'll be centrally located in Greenville, within a 5-minute drive of Haywood Mall and St. Francis ...
Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is AU$237 per night from 24 May to 25 May
AU$237
24 May - 25 May
includes taxes & fees
With a stay at Hyatt Regency Greenville, you'll be centrally located in Greenville, within a 10-minute walk of The Peace Center and Falls Park on the Reedy.
Opens in a new windowHyatt Regency Greenville
Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown

3 out of 5
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
The price is AU$205 per night from 24 May to 25 May
AU$205
24 May - 25 May
includes taxes & fees
Hyatt Place Greenville Downtown is in the heart of Greenville, within a 5-minute walk of The Peace Center and Falls Park on the Reedy.
Opens in a new windowHyatt Place Greenville Downtown
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
The price is AU$168 per night from 24 May to 25 May
AU$168
24 May - 25 May
includes taxes & fees
With a stay at Best Western Plus Clemson Hotel & Conference Center in Clemson, you'll be within a 5-minute drive of Memorial Stadium and Clemson University.
Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Don't see what you're looking for?
See all available properties in Upstate South Carolina
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.

Upstate South Carolina hotels essential information

Accommodation
3,052 hotels
Lowest Price
AU$127
Highest Price
AU$545
Popular hotels
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG, Embassy Suites Greenville Golf Resort & Conference Center, Grand Bohemian Lodge Greenville, Autograph Collection, Hilton Greenville, Hotel Hartness, Best Western Plus Greenville I-385 Inn & Suites, Hyatt Regency Greenville, Hyatt Place Greenville Downtown, Best Western Plus Clemson Hotel & Conference Center

Most recent Upstate South Carolina hotel reviews

Top Picks

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.