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Cheap Defiance hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
The price is AU$148 per night from 22 Dec to 23 Dec
AU$148
22 Dec - 23 Dec
includes taxes & fees
A stay at Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham places you in the heart of Fenton, within a 5-minute drive of SSM Health St. Clare Hospital ...
Opens in a new windowHeritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is AU$228 per night from 18 Jan to 19 Jan
AU$228
18 Jan - 19 Jan 2026
includes taxes & fees
Located in Maryland Heights, Hollywood Casino & Hotel St. Louis is on a river, just a 3-minute walk from Hollywood Casino and a 4-minute drive from Hollywood ...
Opens in a new windowHollywood Casino & Hotel St. Louis
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
2801 Fountain Pl Wildwood MO
Fully refundableReserve now, pay when you stay
Located in Wildwood, The Wildwood Hotel is in the mountains, a 3-minute drive from Wildwood Dog Park and 6 minutes from Dr. Edmund A. Babler Memorial State ...
Opens in a new windowThe Wildwood Hotel
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Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
The price is AU$293 per night from 21 Dec to 22 Dec
AU$293
21 Dec - 22 Dec
includes taxes & fees
A stay at Ameristar Casino Resort and Spa places you in the heart of St. Charles, steps from Ameristar Casino St. Charles and a 4-minute drive from Family ...
Opens in a new windowAmeristar Casino Resort and Spa
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3 out of 5
15431 Conway Rd Chesterfield MO
Fully refundableReserve now, pay when you stay
The price is AU$152 per night from 24 Dec to 25 Dec
AU$152
24 Dec - 25 Dec
includes taxes & fees
When you stay at Sonesta ES Suites St. Louis - Chesterfield in Chesterfield, you'll be in the suburbs, within a 5-minute drive of Sophia M. Sachs Butterfly House ...
Opens in a new windowSonesta ES Suites St. Louis - Chesterfield
La Quinta Inn & Suites by Wyndham St. Louis Westport

La Quinta Inn & Suites by Wyndham St. Louis Westport

3 out of 5
11805 Lackland Rd Maryland Heights MO
Fully refundableReserve now, pay when you stay
The price is AU$143 per night from 28 Dec to 29 Dec
AU$143
28 Dec - 29 Dec
includes taxes & fees
When you stay at La Quinta Inn & Suites by Wyndham St. Louis Westport in Maryland Heights, you'll be in the business district, within a 15-minute drive of Ameristar ...
Opens in a new windowLa Quinta Inn & Suites by Wyndham St. Louis Westport
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

3 out of 5
13639 Riverport Dr Maryland Heights MO
Fully refundableReserve now, pay when you stay
The price is AU$125 per night from 24 Dec to 25 Dec
AU$125
24 Dec - 25 Dec
includes taxes & fees
With a stay at Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West in Maryland Heights, you'll be near the airport, within a 10-minute drive ...
Opens in a new windowLarkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

3 out of 5
1425 South 5th Street St. Charles MO
Fully refundableReserve now, pay when you stay
The price is AU$155 per night from 21 Dec to 22 Dec
AU$155
21 Dec - 22 Dec
includes taxes & fees
When you stay at Best Western Plus The Charles Hotel in St. Charles, you'll be in the historical district, within a 15-minute walk of Ameristar Casino St. Charles ...
Opens in a new windowBest Western Plus The Charles Hotel
Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

3.5 out of 5
11228 Lone Eagle Dr Bridgeton MO
Fully refundable
The price is AU$231 per night from 15 Jan to 16 Jan
AU$231
15 Jan - 16 Jan 2026
includes taxes & fees
Located in Bridgeton, Crowne Plaza St. Louis Airport by IHG is in the suburbs, within a 10-minute drive of Hollywood Casino Amphitheatre and Westport Plaza.
Opens in a new windowCrowne Plaza St. Louis Airport by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Defiance, St. Louis

Forget about spiritual fulfilment or a big bank account. Real happiness is packing your bag for a getaway in St. Louis! If you’re on your way to this exciting city, consider staying in Defiance, 50 kilometres from the centre.

The best place to kick-start your grand adventure is the Gateway Arch, St. Louis' top attraction.

If you and your BFFs are looking for a decent meal but can't be bothered travelling too far away, why not try Piazza Deli & Pizzeria? It's practically next door.

Accommodation options near Defiance

You and the gang having problems finding accommodation in Defiance? If so, the Americas Best Value Inn in Lake St Louis and the Staybridge Suites O'Fallon Chesterfield in O'Fallon are nearby alternatives that are worth looking into.

So, what are you waiting for? It's time to pick out your perfect Defiance accommodations, experiences and flights. And don't forget to tag us in your breathtaking #IntrepidTraveller snaps!

Defiance hotels essential information

Accommodation
858 hotels
Lowest Price
AU$125
Highest Price
AU$293
Popular hotels
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, Hollywood Casino & Hotel St. Louis, The Wildwood Hotel, Ameristar Casino Resort and Spa, Sonesta ES Suites St. Louis - Chesterfield, La Quinta Inn & Suites by Wyndham St. Louis Westport, Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West, Best Western Plus The Charles Hotel, Crowne Plaza St. Louis Airport by IHG

Most recent Defiance hotel reviews

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^Subject to availability and chosen travel dates.