Book Holiday Homes in La Mesa

Start date: Check-in selected.
To Date
End date: Check-out

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in La Mesa

December Specials/Pool/Views/Corporate Retreats

December Specials/Pool/Views/Corporate Retreats

La Jolla
With a stay at this vacation home in La Jolla (Bird Rock), you'll be within a 5-minute drive of Mission Bay and Mission Beach Boardwalk.
Opens in a new windowDecember Specials/Pool/Views/Corporate Retreats
Beach Bungalow Parking 2blocks to Beach

Beach Bungalow Parking 2blocks to Beach

San Diego
With a stay at this vacation home in San Diego (Ocean Beach), you'll be within a 10-minute drive of Hotel Circle and University of San Diego.
Opens in a new windowBeach Bungalow Parking 2blocks to Beach
Family Game Room with Wet Bar, Pool Table/ Ping Pong Darts and more!

Family Game Room with Wet Bar, Pool Table/ Ping Pong Darts and more!

San Diego
With a stay at this vacation home in San Diego (Linda Vista), you'll be within a 5-minute drive of Hotel Circle and University of San Diego.
Opens in a new windowFamily Game Room with Wet Bar, Pool Table/ Ping Pong Darts and more!
Save an average of 15% on thousands of hotels when you're signed in
Ocean View! One house to Beach, Clean and Spacious --South Mission

Ocean View! One house to Beach, Clean and Spacious --South Mission

San Diego
With a stay at this vacation home, you'll be centrally located in San Diego, just a 3-minute walk from Mission Beach and 11 minutes by foot from Belmont ...
Opens in a new windowOcean View! One house to Beach, Clean and Spacious --South Mission
North Pacific Beach Retreat!

North Pacific Beach Retreat!

San Diego
With a stay at this vacation home in San Diego (Pacific Beach), you'll be within a 5-minute drive of Mission Bay and Mission Beach Boardwalk.
Opens in a new windowNorth Pacific Beach Retreat!
Spanish Casita in the Village of La Jolla - Walk to Everything

Spanish Casita in the Village of La Jolla - Walk to Everything

La Jolla
With a stay at this vacation home in La Jolla (Village of La Jolla), you'll be within a 5-minute drive of La Jolla Cove and University of California, San ...
Opens in a new windowSpanish Casita in the Village of La Jolla - Walk to Everything
Beachcomber Bliss Sleeps 4 Free Parking 2BLKS to Ocean

Beachcomber Bliss Sleeps 4 Free Parking 2BLKS to Ocean

San Diego
Located in San Diego (Ocean Beach), this vacation home is within a 10-minute drive of Hotel Circle and University of San Diego.
Opens in a new windowBeachcomber Bliss Sleeps 4 Free Parking 2BLKS to Ocean
New! The Gem of Mission Hills: Luxury 5BR Home with Luxe Amenities and views"

New! The Gem of Mission Hills: Luxury 5BR Home with Luxe Amenities and views"

San Diego
With a stay at this vacation home, you'll be centrally located in San Diego, within a 5-minute drive of Marine Corps Recruit Depot and Mission Bay.
Opens in a new windowNew! The Gem of Mission Hills: Luxury 5BR Home with Luxe Amenities and views"
Enchanting 2-bedroom house with WiFi in sunny Bird Rock - La Jolla

Enchanting 2-bedroom house with WiFi in sunny Bird Rock - La Jolla

San Diego
With a stay at this vacation home in La Jolla (Bird Rock), you'll be within a 5-minute drive of Mission Bay and Mission Beach Boardwalk.
Opens in a new windowEnchanting 2-bedroom house with WiFi in sunny Bird Rock - La Jolla
Don't see what you're looking for?
See all available properties in La Mesa
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

La Mesa Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our La Mesa vacation homes are the perfect way for you to wing it.

Holiday houses in La Mesa let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of La Mesa in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local La Mesa adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in La Mesa with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of La Mesa vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

La Mesa Holiday Homes essential information

Accommodation
3197 Holiday Homes
Lowest Price
AU$144
Highest Price
AU$510
Popular accommodation
December Specials/Pool/Views/Corporate Retreats, Beach Bungalow Parking 2blocks to Beach, Family Game Room with Wet Bar, Pool Table/ Ping Pong Darts and more!, Ocean View! One house to Beach, Clean and Spacious --South Mission, North Pacific Beach Retreat!, Spanish Casita in the Village of La Jolla - Walk to Everything, Beachcomber Bliss Sleeps 4 Free Parking 2BLKS to Ocean, New! The Gem of Mission Hills: Luxury 5BR Home with Luxe Amenities and views", Enchanting 2-bedroom house with WiFi in sunny Bird Rock - La Jolla

Top trending hotels in La Mesa

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$231 per night from 5 Nov to 6 Nov
AU$231
5 Nov - 6 Nov
includes taxes & fees
With a stay at Hampton Inn & Suites by Hilton San Diego SeaWorld in San Diego (Point Loma), you'll be within a 15-minute walk of Pechanga Arena and Old Town ...
Opens in a new windowHampton Inn & Suites by Hilton San Diego SeaWorld
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$510 per night from 29 Oct to 30 Oct
AU$510
29 Oct - 30 Oct
includes taxes & fees
With a stay at Manchester Grand Hyatt San Diego in San Diego (Downtown San Diego), you'll be a 4-minute walk from Seaport Village and 7 minutes by foot from ...
Opens in a new windowManchester Grand Hyatt San Diego
Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor

3.5 out of 5
San Diego
The price is AU$144 per night from 28 Oct to 29 Oct
AU$144
28 Oct - 29 Oct
includes taxes & fees
With a stay at Comfort Inn San Diego Airport At The Harbor, you'll be centrally located in San Diego, within a 5-minute drive of San Diego Bay and Shelter ...
Opens in a new windowComfort Inn San Diego Airport At The Harbor
Save an average of 15% on thousands of hotels when you're signed in
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
With a stay at Handlery Hotel in San Diego (Mission Valley), you'll be within a 5-minute drive of Hotel Circle and University of San Diego.
Opens in a new windowHandlery Hotel
Don't see what you're looking for?
See all available properties in La Mesa
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.