Find Downtown Clayton hotels

Start date: Check-in selected.
To Date
End date: Check-out

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Downtown Clayton

Top trending hotels in Downtown Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$182 per night from 12 Oct to 13 Oct
AU$182
12 Oct - 13 Oct
includes taxes & fees
With a stay at Clayton Plaza Hotel & Extended Stay in St. Louis (Clayton), you'll be within a 5-minute drive of Washington University in St. Louis and Forest ...
Opens in a new windowClayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave, St. Louis, MO
The price is AU$217 per night from 26 Oct to 27 Oct
AU$217
26 Oct - 27 Oct
includes taxes & fees
With a stay at AC Hotel St. Louis Clayton in St. Louis (Clayton), you'll be a 4-minute drive from Washington University in St. Louis and 5 minutes from Forest ...
Opens in a new windowAC Hotel St. Louis Clayton
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave, St. Louis, MO
The price is AU$296 per night from 28 Sept to 29 Sept
AU$296
28 Sept - 29 Sept
includes taxes & fees
Located in St. Louis (Clayton), Le Méridien St. Louis Clayton is within a 5-minute drive of Washington University in St. Louis and Forest Park.
Opens in a new windowLe Méridien St. Louis Clayton
Save an average of 15% on thousands of hotels when you're signed in
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$1,032 per night from 28 Sept to 29 Sept
AU$1,032
28 Sept - 29 Sept
includes taxes & fees
With a stay at The Ritz-Carlton, St. Louis, you'll be centrally located in St. Louis, within a 5-minute drive of Washington University in St. Louis and Forest ...
Opens in a new windowThe Ritz-Carlton, St. Louis
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$227 per night from 18 Oct to 19 Oct
AU$227
18 Oct - 19 Oct
includes taxes & fees
With a stay at Renaissance St. Louis Airport Hotel in St. Louis (Berkeley), you'll be within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar ...
Opens in a new windowRenaissance St. Louis Airport Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln, St. Ann, MO
Fully refundableReserve now, pay when you stay
The price is AU$162 per night from 20 Oct to 21 Oct
AU$162
20 Oct - 21 Oct
includes taxes & fees
With a stay at Pear Tree Inn St. Louis Airport, you'll be centrally located in St. Ann, within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar ...
Opens in a new windowPear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$214 per night from 19 Oct to 20 Oct
AU$214
19 Oct - 20 Oct
includes taxes & fees
With a stay at Drury Plaza Hotel St. Louis at the Arch, you'll be centrally located in St. Louis, just a 5-minute walk from Gateway Arch and 6 minutes by foot ...
Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$225 per night from 2 Oct to 3 Oct
AU$225
2 Oct - 3 Oct
includes taxes & fees
A stay at Hyatt Regency St. Louis at The Arch places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Busch Stadium.
Opens in a new windowHyatt Regency St. Louis at The Arch
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive, Fenton, MO
Fully refundableReserve now, pay when you stay
The price is AU$158 per night from 12 Oct to 13 Oct
AU$158
12 Oct - 13 Oct
includes taxes & fees
A stay at Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham places you in the heart of Fenton, within a 5-minute drive of LIFECHURCH and SSM Health ...
Opens in a new windowHeritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Don't see what you're looking for?
See all available properties in Downtown Clayton
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Downtown Clayton Hotels

Haven’t you been dying to check out that swanky new coffee shop? What about the recently opened bar serving drinks in mason jars? And let’s not forget about the barber shops willing to give you a shaved-on-the-sides, long-on-top cut whenever you want. Don’t worry; we’ll help you find the best deals at hotels in Downtown Clayton.

This hip new ’hood will charm the-you-know-what off you. Downtown Clayton hotels are comfortable and affordable, and many offer amenities like room service for those late-night meals, as well as a pool to swim in. Some of these hotels will also have you near great shopping such as souvenir shops, clothing boutiques and everything in between. Don’t feel like leaving the hotel for dinner and drinks? Hang out in the lobby bar and meet some of your fellow travellers—you never what kinds of stories they have in their memory log.

There’s no point in going somewhere if you’re not going to stay where all the action is. lastminute.com.au gets you the best offers on where to stay in Downtown Clayton so you don’t have to waste endless hours searching online. The trip of a lifetime is at your fingertips. Click and go!

Downtown Clayton hotels essential information

Accommodation
1,734 hotels
Lowest Price
AU$158
Highest Price
AU$1,032
Popular hotels
Clayton Plaza Hotel & Extended Stay, AC Hotel St. Louis Clayton, Le Méridien St. Louis Clayton, The Ritz-Carlton, St. Louis, Drury Plaza Hotel St. Louis at the Arch, Hyatt Regency St. Louis at The Arch, Renaissance St. Louis Airport Hotel, Pear Tree Inn St. Louis Airport, Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Most recent Downtown Clayton hotel reviews

More ways to explore Downtown Clayton