Book Southwest Illinois hotels
More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)
We keep it easy with the option to pay now or later on select accommodation
Book up 'til the last second - millions of rooms to crash tonight^
Check hotel availability in Southwest Illinois
Tomorrow night
Check prices in Southwest Illinois for tomorrow night, 29 Sept - 30 SeptCheap Southwest Illinois hotels

Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is AU$163 per night from 5 Oct to 6 Oct
AU$163
5 Oct - 6 Oct
includes taxes & fees
A stay at Drury Plaza Hotel Mt. Vernon places you in the heart of Mount Vernon, within a 5-minute drive of King City Square Shopping Center and Crossroads Community ...

Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
The price is AU$119 per night from 26 Oct to 27 Oct
AU$119
26 Oct - 27 Oct
includes taxes & fees
With a stay at Quality Inn & Suites near St. Louis and I-255, you'll be centrally located in East St. Louis, within a 15-minute drive of Busch Stadium and St. ...

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
The price is AU$161 per night from 2 Oct to 3 Oct
AU$161
2 Oct - 3 Oct
includes taxes & fees
Located in Fairview Heights, Drury Inn & Suites St. Louis Fairview Heights is within a 15-minute drive of Mississippi River and America's Center Convention ...
Save an average of 15% on thousands of hotels when you're signed in

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is AU$90 per night from 5 Oct to 6 Oct
AU$90
5 Oct - 6 Oct
includes taxes & fees
Located in O'Fallon, Super 8 by Wyndham O'Fallon is within a 10-minute drive of Shiloh Dog Park and Scott Air Force Base.

Drury Inn & Suites Marion
2706 W DeYoung St, Marion, IL
Fully refundableReserve now, pay when you stay
The price is AU$172 per night from 12 Oct to 13 Oct
AU$172
12 Oct - 13 Oct
includes taxes & fees
A stay at Drury Inn & Suites Marion places you in the heart of Marion, within a 5-minute drive of Kokopelli Golf Club and Marion Stadium.

Best Western Plus Pontoon Beach
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is AU$153 per night from 30 Sept to 1 Oct
AU$153
30 Sept - 1 Oct
includes taxes & fees
With a stay at Best Western Plus Pontoon Beach in Granite City, you'll be near the airport, within a 15-minute drive of Mississippi River and Horseshoe Lake ...

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
136 Regency Park, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is AU$125 per night from 26 Oct to 27 Oct
AU$125
26 Oct - 27 Oct
includes taxes & fees
Located in O'Fallon, La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis is within a 5-minute drive of O'Fallon Family Sports Park and HSHS St. Elizabeth's ...

Red Lion Inn & Suites Pontoon Beach
1240 E Chain Of Rocks Rd, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is AU$119 per night from 29 Sept to 30 Sept
AU$119
29 Sept - 30 Sept
includes taxes & fees
With a stay at Red Lion Inn & Suites Pontoon Beach in Granite City, you'll be within a 10-minute drive of Horseshoe Lake State Park and Lewis and Clark Interpretive ...

The Principal Hotel
310 S Main St, Columbia, IL
Fully refundableReserve now, pay when you stay
The price is AU$180 per night from 29 Sept to 30 Sept
AU$180
29 Sept - 30 Sept
includes taxes & fees
With a stay at The Principal Hotel in Columbia, you'll be 8.9 mi (14.3 km) from Missouri Civil War Museum and 11.9 mi (19.2 km) from River City Casino.
Don't see what you're looking for?
See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
**Terms and Conditions apply.
^Subject to availability and chosen travel dates.
Southwest Illinois hotels essential information
Accommodation | 714 hotels |
---|---|
Lowest Price | AU$90 |
Highest Price | AU$180 |
Popular hotels | Drury Plaza Hotel Mt. Vernon, Quality Inn & Suites near St. Louis and I-255, Drury Inn & Suites St. Louis Fairview Heights, Super 8 by Wyndham O'Fallon, Drury Inn & Suites Marion, Best Western Plus Pontoon Beach, La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis, Red Lion Inn & Suites Pontoon Beach, The Principal Hotel |
Most recent Southwest Illinois hotel reviews

lastminute.com.au Verified Review
5 / 5
Cozy and comforting
A verified traveller stayed at Quality Inn & Suites Caseyville - St. Louis
Posted 6 days ago
More ways to explore Southwest Illinois
Top picks
Hotels
- All Inclusive Hotels in Maui
- Boutique Hotels in Downtown Chicago
- Pet Friendly Hotels in Harvey
- Aspen Snowmass Accommodation
- All Inclusive Hotels in Oahu
- Hawaii Island Accommodation
- Hotels in Downtown Chicago
- Countryside Accommodation
- Kauai Accommodation
- Apartment Hotels in Hawaii Island
- North Shore Accommodation
- Luxury Hotels in Hawaii Island
- Maui Accommodation
- Family Hotels in Oahu
- Family Hotels in Maui
- Oahu Accommodation
- Napa Valley Accommodation
- Rosemont Accommodation
Flights
**Terms and Conditions apply.
^Subject to availability and chosen travel dates.