Book Holiday Homes in Semmes

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Featured Holiday Homes in Semmes

Welcome to House on Hallett.  A historic home less than a mile from downtown

Welcome to House on Hallett. A historic home less than a mile from downtown

Mobile AL
With a stay at this vacation home in Mobile (Old Dauphin Way Historic District), you'll be within a 5-minute drive of Mobile Cruise Terminal and Dauphin ...
Opens in a new windowWelcome to House on Hallett. A historic home less than a mile from downtown
Magnolia House - charming 3-bedroom house in Semmes, Alabama

Magnolia House - charming 3-bedroom house in Semmes, Alabama

Semmes AL
Located in Semmes, this vacation home is within a 5-minute drive of Miller Park and Semmes Municipal Park.
Opens in a new windowMagnolia House - charming 3-bedroom house in Semmes, Alabama
4 Bedroom , Lavish Euro Style Boutique ,Home Alabama

4 Bedroom , Lavish Euro Style Boutique ,Home Alabama

Mobile AL
The price is AU$402 per night from 4 Jan to 5 Jan
AU$402
4 Jan - 5 Jan 2026
includes taxes & fees
With a stay at this vacation home in Mobile (Brookwood), you'll be within a 10-minute drive of Mobile Cruise Terminal and Herndon Park.
Opens in a new window4 Bedroom , Lavish Euro Style Boutique ,Home Alabama
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Central, Wonderful Porch & Yard! Hazel Hideaway

Central, Wonderful Porch & Yard! Hazel Hideaway

Mobile AL
With a stay at this vacation home, you'll be centrally located in Mobile, within a 10-minute drive of Mobile Cruise Terminal and Dauphin Street.
Opens in a new windowCentral, Wonderful Porch & Yard! Hazel Hideaway
Cozy and quiet getaway close to Park & Bay

Cozy and quiet getaway close to Park & Bay

Mobile AL
With a stay at this vacation home in Mobile (Driftwood), you'll be within a 15-minute drive of Mobile Cruise Terminal and Mobile Bay.
Opens in a new windowCozy and quiet getaway close to Park & Bay
Beautiful 5 bedroom home w/ fireplace. Close to all attractions in Mobile area

Beautiful 5 bedroom home w/ fireplace. Close to all attractions in Mobile area

Mobile AL
With a stay at this vacation home in Mobile, you'll be within a 5-minute drive of Mobile Public Library, Davis Avenue Branch and University of South ...
Opens in a new windowBeautiful 5 bedroom home w/ fireplace. Close to all attractions in Mobile area
Charming Historic Midtown Home

Charming Historic Midtown Home

Mobile AL
With a stay at this vacation home, you'll be centrally located in Mobile, within a 15-minute drive of Mobile Cruise Terminal and University of South ...
Opens in a new windowCharming Historic Midtown Home
Cypress Grove - Dog River - Heated Pool

Cypress Grove - Dog River - Heated Pool

Mobile AL
With a stay at this vacation home in Mobile, you'll be within a 15-minute drive of Mobile Cruise Terminal and University of South Alabama.
Opens in a new windowCypress Grove - Dog River - Heated Pool
Spacious Home n Garden

Spacious Home n Garden

Spanish Fort AL
With a stay at this vacation home in Spanish Fort, you'll be within a 15-minute drive of Mobile Cruise Terminal and Mobile Bay.
Opens in a new windowSpacious Home n Garden
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Semmes Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Semmes vacation homes are the perfect way for you to wing it.

Holiday houses in Semmes let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Semmes in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Semmes adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Semmes with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Semmes vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Semmes Holiday Homes essential information

Accommodation
133 Holiday Homes
Lowest Price
AU$138
Highest Price
AU$402
Popular accommodation
Welcome to House on Hallett. A historic home less than a mile from downtown, Magnolia House - charming 3-bedroom house in Semmes, Alabama, 4 Bedroom , Lavish Euro Style Boutique ,Home Alabama, Central, Wonderful Porch & Yard! Hazel Hideaway, Cozy and quiet getaway close to Park & Bay, Beautiful 5 bedroom home w/ fireplace. Close to all attractions in Mobile area , Charming Historic Midtown Home , Cypress Grove - Dog River - Heated Pool, Spacious Home n Garden

Top trending hotels in Semmes

The Admiral, Downtown Historic District

The Admiral, Downtown Historic District

4 out of 5
251 Government Street Mobile AL
Fully refundableReserve now, pay when you stay
The price is AU$230 per night from 4 Jan to 5 Jan
AU$230
4 Jan - 5 Jan 2026
includes taxes & fees
With a stay at The Admiral, Downtown Historic District in Mobile (Mobile Central Business District), you'll be within a 10-minute walk of Mobile Cruise Terminal ...
Opens in a new windowThe Admiral, Downtown Historic District
Hampton Inn & Suites Mobile I-65@ Airport Blvd

Hampton Inn & Suites Mobile I-65@ Airport Blvd

3 out of 5
1028 W I-65 Service Rd S Mobile AL
Fully refundableReserve now, pay when you stay
The price is AU$156 per night from 30 Dec to 31 Dec
AU$156
30 Dec - 31 Dec
includes taxes & fees
With a stay at Hampton Inn & Suites Mobile I-65@ Airport Blvd in Mobile (Bolton), you'll be within a 15-minute drive of Mobile Cruise Terminal and Herndon ...
Opens in a new windowHampton Inn & Suites Mobile I-65@ Airport Blvd
Holiday Inn Mobile-Dwtn/Hist. District by IHG

Holiday Inn Mobile-Dwtn/Hist. District by IHG

3 out of 5
301 Government St Mobile AL
Fully refundable
The price is AU$174 per night from 4 Jan to 5 Jan
AU$174
4 Jan - 5 Jan 2026
includes taxes & fees
Holiday Inn Mobile-Dwtn/Hist. District by IHG is in the heart of Mobile, within a 5-minute walk of Cathedral of the Immaculate Conception and Mobile Civic ...
Opens in a new windowHoliday Inn Mobile-Dwtn/Hist. District by IHG
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Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

2.5 out of 5
12000 Cypress Way Spanish Fort AL
Fully refundableReserve now, pay when you stay
The price is AU$138 per night from 1 Jan to 2 Jan
AU$138
1 Jan - 2 Jan 2026
includes taxes & fees
Located in Spanish Fort, Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore is connected to a shopping center, within a 5-minute drive of Gator Boardwalk ...
Opens in a new windowFairfield Inn & Suites by Marriott Mobile Daphne/ E Shore
Don't see what you're looking for?
See all available properties in Semmes
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.