Book Holiday Homes in Santee

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Featured Holiday Homes in Santee

Lake Marion Lakehouse with 180° lake view

Lake Marion Lakehouse with 180° lake view

Elloree
Located in Elloree, this vacation home is on the waterfront, within a 15-minute drive of Lake Marion and Orangeburg County Library Mentor Branch.
Opens in a new windowLake Marion Lakehouse with 180° lake view
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Summerton
When you stay at this vacation home in Summerton, you'll be on the beach and 9 minutes by foot from Lake Marion.
Opens in a new windowSANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

4 out of 5
401 Bass Drive, Santee, SC
With a stay at Wyndham Vacation Resorts Lake Marion in Santee, you'll be within a 15-minute walk of Santee State Park and Santee Cooper Country Club.
Opens in a new windowWyndham Vacation Resorts Lake Marion
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Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!

Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!

Summerton
With a stay at this vacation home in Summerton, you'll be on the waterfront, a 2-minute walk from Lake Marion and a 3-minute drive from Goat Island.
Opens in a new windowBeautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.

Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.

Summerton
Located in Summerton, this vacation home is on the waterfront, within a 10-minute drive of Taw Caw Creek Park and Taw Caw Creek.
Opens in a new windowWaterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.
Beautiful Cottage between Lake Moultrie and Lake Marion

Beautiful Cottage between Lake Moultrie and Lake Marion

Cross
Located in Cross, this vacation home is on the waterfront, a 2-minute drive from Lake Marion and 9 minutes from Lake Moultrie.
Opens in a new windowBeautiful Cottage between Lake Moultrie and Lake Marion
Deep water Lake Marion house.  4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Summerton
Located in Summerton, this vacation home is on the waterfront, within a 15-minute drive of Lake Marion and Pine Island.
Opens in a new windowDeep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Beautiful lake home to make your family vacation extra special!

Beautiful lake home to make your family vacation extra special!

Summerton
When you stay at this vacation home in Summerton, you'll be 4 minutes by foot from Lake Marion.
Opens in a new windowBeautiful lake home to make your family vacation extra special!
Sweet Marion - Dock + Boat Ramp + Hot Tub!

Sweet Marion - Dock + Boat Ramp + Hot Tub!

Summerton
The price is AU$727 per night from 19 Oct to 20 Oct
AU$727
19 Oct - 20 Oct
includes taxes & fees
Located in Summerton, this vacation home is within a 5-minute drive of Taw Caw Creek Park and Goat Island.
Opens in a new windowSweet Marion - Dock + Boat Ramp + Hot Tub!
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santee Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Santee vacation homes are the perfect way for you to wing it.

Holiday houses in Santee let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Santee in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Santee adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Santee with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Santee vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Santee Holiday Homes essential information

Accommodation
83 Holiday Homes
Lowest Price
AU$125
Highest Price
AU$727
Popular accommodation
Lake Marion Lakehouse with 180° lake view, SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable, Wyndham Vacation Resorts Lake Marion, Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!, Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant., Beautiful Cottage between Lake Moultrie and Lake Marion , Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS, Beautiful lake home to make your family vacation extra special!, Sweet Marion - Dock + Boat Ramp + Hot Tub!

Top trending hotels in Santee

Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$168 per night from 25 Sept to 26 Sept
AU$168
25 Sept - 26 Sept
includes taxes & fees
Located in Santee, Tru By Hilton Santee is within a 5-minute drive of Santee Cooper Country Club and Santee National Golf Club.
Opens in a new windowTru By Hilton Santee
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$125 per night from 21 Sept to 22 Sept
AU$125
21 Sept - 22 Sept
includes taxes & fees
A stay at Baymont by Wyndham Santee places you in the heart of Santee, within a 5-minute drive of Santee Cooper Country Club and Santee National Golf Club.
Opens in a new windowBaymont by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$208 per night from 25 Sept to 26 Sept
AU$208
25 Sept - 26 Sept
includes taxes & fees
With a stay at Fairfield Inn & Suites by Marriott Santee in Santee, you'll be steps from Santee Cooper Country Club and a 3-minute drive from Santee National ...
Opens in a new windowFairfield Inn & Suites by Marriott Santee
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd, Santee, SC
Fully refundable
The price is AU$213 per night from 20 Oct to 21 Oct
AU$213
20 Oct - 21 Oct
includes taxes & fees
Located in Santee, Holiday Inn Santee by IHG is in a rural location, within a 5-minute drive of Santee Cooper Country Club and Santee National Golf Club.
Opens in a new windowHoliday Inn Santee by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.