Book Santa Isabel hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Santa Isabel

Cheap Santa Isabel hotels

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

2 out of 5
Diablo Island Narganá Guna Yala
When you stay at Private Ocean-Front Cabin with private bathroom on San Blas Island in San Blas Islands, you'll be steps from Isla Diablo.
Opens in a new windowPrivate Ocean-Front Cabin with private bathroom on San Blas Island
Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS

3 out of 5
El Porvenir Narganá Guna Yala
Fully refundableReserve now, pay when you stay
The price is AU$3,103 per night from 9 June to 10 June
AU$3,103
9 June - 10 June
includes taxes & fees
With a stay at Cocoloco - Catamaran Lagoon 52F SAN BLAS in San Blas Islands, you'll be on the beach and close to Porvenir Museum.
Opens in a new windowCocoloco - Catamaran Lagoon 52F SAN BLAS
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

Santa Isabel Colon
With a stay at this villa in Palenque, you'll be on the beach, and 15.6 mi (25.1 km) from Portobelo National Park and 23.7 mi (38.1 km) from Isla Mamey.
Opens in a new windowBEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
Save an average of 15% on thousands of hotels when you're signed in
Private wood Cabins on San Blas island - private bathroom

Private wood Cabins on San Blas island - private bathroom

2 out of 5
Wailidup Island Narganá Guna Yala
When you stay at Private wood Cabins on San Blas island - private bathroom in San Blas Islands, you'll be on the beach and steps from Isla Chichime.
Opens in a new windowPrivate wood Cabins on San Blas island - private bathroom
Caribbean Haven Of Nature 'Preci Beach'

Caribbean Haven Of Nature 'Preci Beach'

Nombre de Dios Colon
With a stay at this vacation home in Nombre de Dios, you'll be on the beach, and 10.9 mi (17.6 km) from Portobelo National Park and 19 mi (30.6 km) from Isla ...
Opens in a new windowCaribbean Haven Of Nature 'Preci Beach'
Cabins on paradise San Blas island

Cabins on paradise San Blas island

2 out of 5
9.587566, -78.879820 Narganá San Blas
Fully refundableReserve now, pay when you stay
The price is AU$409 per night from 15 May to 16 May
AU$409
15 May - 16 May
includes taxes & fees
When you stay at Cabins on paradise San Blas island in Narganá, you'll be within a short 4-minute drive from Museum.
Opens in a new windowCabins on paradise San Blas island
 Paradise Over the Water Cabins in San Blas

Paradise Over the Water Cabins in San Blas

2.5 out of 5
G4V2 48 Narganá Guna Yala
When you stay at this cabin in San Blas Islands, you'll be on the beach and steps from Porvenir Museum.
Opens in a new window Paradise Over the Water Cabins in San Blas
Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand

Palenque Provincia de Colón
With a stay at this cottage in Palenque, you'll be on the beach, and 15.2 mi (24.4 km) from Portobelo National Park and 23.3 mi (37.4 km) from Isla Mamey.
Opens in a new windowCaribbean getaway: beach cottage just on the sand
Trips Guna Yala

Trips Guna Yala

2 out of 5
Urgandi, Mamardub Narganá Guna Yala
When you stay at Trips Guna Yala in Narganá, you'll be convenient to Museum.
Opens in a new windowTrips Guna Yala
Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Isabel

Eager to stay close to Santa Isabel? With just 1 hotel within a 10-kilometre radius of the centre, you'll have to move fast!

As close to the city centre as you can get, Coral Lodge is a fabulous place to chill out after a hectic day of amazing adventures.

One more option is the Coco Blanco, which is an awesome option if you don't mind travelling 25 kilometres to the centre.

Looking for more things to do? Spend the day checking out the San Felipe Church and Portobelo National Park. You'll find them in Portobelo, 55 kilometres to the west of Santa Isabel. The El Otro Lado and ScubaPortobello - Hostel are just some of the long and short-stay options here. Or, you could consider staying in Mechi, 60 kilometres to the west of Santa Isabel, where you'll find the Panama Divers & Octopus Garden Dive Center and Rancho Juancho. If you stay in Mechi, be sure to check out Fuerte San Jerónimo and the Real Aduana de Portobelo.

Panama City sits 75 kilometres from Santa Isabel. It is home to a range of accommodations, including the American Trade Hotel and Las Clementinas. Things to see and do in and around Panama City include Multiplaza Pacific Mall and Multicentro Panama.

Tired of plane food? Dying for a bit of privacy? Then you'd be nuts not to see if you can snag a room at the Riande Aeropuerto Hotel & Casino or the Crowne Plaza Panama Airport. Both are a stone's throw from Tocumen International Airport, 55 kilometres from Santa Isabel's centre.

Santa Isabel hotels essential information

Accommodation
40 hotels
Lowest Price
AU$409
Highest Price
AU$3,103
Popular hotels
Private Ocean-Front Cabin with private bathroom on San Blas Island, Cocoloco - Catamaran Lagoon 52F SAN BLAS, BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES, Private wood Cabins on San Blas island - private bathroom, Caribbean Haven Of Nature 'Preci Beach', Cabins on paradise San Blas island, Paradise Over the Water Cabins in San Blas, Caribbean getaway: beach cottage just on the sand, Trips Guna Yala

Most recent Santa Isabel hotel reviews

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.