Book Holiday Homes in Panacea

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Featured Holiday Homes in Panacea

Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!

Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!

2 out of 5
Crawfordville FL
The price is AU$539 per night from 21 Dec to 22 Dec
AU$539
21 Dec - 22 Dec
includes taxes & fees
With a stay at this vacation home in Crawfordville, you'll be within a 15-minute drive of Shell Point Beach and Wildwood Golf Club.
Opens in a new windowCanal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!
Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

Alligator Point FL
Located in Alligator Point, this vacation home is by the ocean, within a 15-minute drive of Bald Point State Park and Public Beach Access.
Opens in a new windowPrivate Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +
Coastal Getaway on canal-steps to the beach

Coastal Getaway on canal-steps to the beach

Panacea FL
Located in Panacea, this vacation home is by the ocean, a 1-minute drive from Mashes Sand Beach and 8 minutes from Bayside Marina.
Opens in a new windowCoastal Getaway on canal-steps to the beach
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Gulf Coast Getaway: 5BR Home with Private Dock – Keep Your Boat in the Water!

Gulf Coast Getaway: 5BR Home with Private Dock – Keep Your Boat in the Water!

Alligator Point FL
The price is AU$1,567 per night from 2 Jan to 3 Jan
AU$1,567
2 Jan - 3 Jan 2026
includes taxes & fees
Located in Alligator Point, this vacation home is on the waterfront, a 2-minute drive from Public Beach Access and 5 minutes from Alligator Point Beach.
Opens in a new windowGulf Coast Getaway: 5BR Home with Private Dock – Keep Your Boat in the Water!
NEW LISTING!!! 
Welcome to Ohana Shack!
 4BR/4.5BA Private Beachfront Property!

NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!

Panacea FL
Located in Alligator Point, this vacation home is by the ocean, a 1-minute drive from Bald Point State Park and 8 minutes from Public Beach Access.
Opens in a new windowNEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!
BEACHFRONT "Turtles Nest" Delight in Bald Point- New Listing w/ Private Beach

BEACHFRONT "Turtles Nest" Delight in Bald Point- New Listing w/ Private Beach

Panacea FL
With a stay at this vacation home in Alligator Point, you'll be within a 15-minute drive of Bald Point State Park and Public Beach Access.
Opens in a new windowBEACHFRONT "Turtles Nest" Delight in Bald Point- New Listing w/ Private Beach
Pet friendly
Kayak with the manatees

Pet friendly Kayak with the manatees

2 out of 5
Crawfordville FL
With a stay at this vacation home in Crawfordville, you'll be within a 10-minute drive of Wakulla Springs State Park and Wildwood Golf Club.
Opens in a new windowPet friendly Kayak with the manatees
Blue Seahorse *Carrabelle/Eastpoint/St. George FL Beachfront* Pet-Friendly**

Blue Seahorse *Carrabelle/Eastpoint/St. George FL Beachfront* Pet-Friendly**

Carrabelle FL
Located in Carrabelle, this vacation home is on the waterfront, within a 5-minute drive of Carrabelle Beach and Crooked River Lighthouse.
Opens in a new windowBlue Seahorse *Carrabelle/Eastpoint/St. George FL Beachfront* Pet-Friendly**
Wakulla River Retreat - a nature lover’s paradise

Wakulla River Retreat - a nature lover’s paradise

Crawfordville FL
Located in Crawfordville, this vacation home is on a river, within a 15-minute drive of Wakulla Springs State Park and Wakulla State Forest.
Opens in a new windowWakulla River Retreat - a nature lover’s paradise
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panacea Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Panacea vacation homes are the perfect way for you to wing it.

Holiday houses in Panacea let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Panacea in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Panacea adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Panacea with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Panacea vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Panacea Holiday Homes essential information

Accommodation
221 Holiday Homes
Lowest Price
AU$539
Highest Price
AU$1,567
Popular accommodation
Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!, Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +, Coastal Getaway on canal-steps to the beach, Gulf Coast Getaway: 5BR Home with Private Dock – Keep Your Boat in the Water!, NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!, BEACHFRONT "Turtles Nest" Delight in Bald Point- New Listing w/ Private Beach, Pet friendly Kayak with the manatees, Blue Seahorse *Carrabelle/Eastpoint/St. George FL Beachfront* Pet-Friendly**, Wakulla River Retreat - a nature lover’s paradise

Top trending hotels in Panacea

Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Panacea FL
The price is AU$675 per night from 3 Jan to 4 Jan
AU$675
3 Jan - 4 Jan 2026
includes taxes & fees
With a stay at this vacation home in Alligator Point, you'll be on the beach, just steps from Public Beach Access and a 3-minute drive from Alligator Point ...
Opens in a new windowSkipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock
The Panacea Motel

The Panacea Motel

2 out of 5
1545 Coastal Hwy Panacea FL
Located in Panacea, The Panacea Motel is in a rural location, within a 5-minute drive of Panacea Springs and Woolley Park.
Opens in a new windowThe Panacea Motel
"Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8

"Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8

Alligator Point FL
With a stay at this vacation home in Alligator Point, you'll be on the beach, just steps from Public Beach Access and a 3-minute drive from Alligator Point ...
Opens in a new window"Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8
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5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

Panacea FL
Located in Alligator Point, this vacation home is by the ocean, within a 15-minute drive of Bald Point State Park and Public Beach Access.
Opens in a new window5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.