Book Holiday Homes in Mesilla

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Featured Holiday Homes in Mesilla

Quaint Southwest Mesilla Home - Pet Friendly

Quaint Southwest Mesilla Home - Pet Friendly

Las Cruces
With a stay at this vacation home in Las Cruces, you'll be within a 10-minute drive of New Mexico State University and Las Cruces Convention Center.
Quaint Southwest Mesilla Home - Pet Friendly
Desert Pool Oasis located in the heart of Las Cruces

Desert Pool Oasis located in the heart of Las Cruces

Las Cruces
With a stay at this vacation home in Las Cruces, you'll be in the mountains, within a 5-minute drive of New Mexico State University and Mesilla Valley Mall.
Desert Pool Oasis located in the heart of Las Cruces
Unique 1-bedroom casita in Mesilla Park with hot tub

Unique 1-bedroom casita in Mesilla Park with hot tub

Las Cruces
With a stay at this vacation home in Las Cruces, you'll be within a 10-minute drive of New Mexico State University and Las Cruces Convention Center.
Unique 1-bedroom casita in Mesilla Park with hot tub
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Hacienda de Horacio a 3 bedroom w/2 king beds, private patio and parking.

Hacienda de Horacio a 3 bedroom w/2 king beds, private patio and parking.

Las Cruces
With a stay at this vacation home in Las Cruces, you'll be within a 5-minute drive of New Mexico State University and Rio Grande Vineyards and Winery.
Hacienda de Horacio a 3 bedroom w/2 king beds, private patio and parking.
Casita Azul, Mesilla Plaza Only Steps Away

Casita Azul, Mesilla Plaza Only Steps Away

Mesilla
With a stay at this vacation home in Mesilla, you'll be on a lake, within a 15-minute drive of New Mexico State University and Mesillia Plaza.
Casita Azul, Mesilla Plaza Only Steps Away
Casa Elena Adobe casita in historic Mesilla

Casa Elena Adobe casita in historic Mesilla

Las Cruces
With a stay at this vacation home in Las Cruces, you'll be within a 15-minute drive of New Mexico State University and San Albino Basilica.
Casa Elena Adobe casita in historic Mesilla
The Francisco and Maria Amador house is in the heart of downtown Las Cruces.

The Francisco and Maria Amador house is in the heart of downtown Las Cruces.

Las Cruces
With a stay at this vacation home in Las Cruces, you'll be within a 15-minute drive of New Mexico State University and Las Cruces Community Theatre.
The Francisco and Maria Amador house is in the heart of downtown Las Cruces.
4 Bedroom Contemporary Model Home

4 Bedroom Contemporary Model Home

Las Cruces
With a stay at this vacation home in Las Cruces, you'll be within a 10-minute drive of New Mexico State University and Aggie Memorial Stadium.
4 Bedroom Contemporary Model Home
⭐️ Western Style Casita w/ 3BR and a Fitness Room plus View to the Mountains

⭐️ Western Style Casita w/ 3BR and a Fitness Room plus View to the Mountains

Las Cruces
With a stay at this vacation home in Las Cruces, you'll be within a 15-minute drive of New Mexico State University and Sonoma Ranch Golf Course.
⭐️ Western Style Casita w/ 3BR and a Fitness Room plus View to the Mountains
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mesilla Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Mesilla vacation homes are the perfect way for you to wing it.

Holiday houses in Mesilla let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Mesilla in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Mesilla adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Mesilla with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Mesilla vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Mesilla Holiday Homes essential information

Accommodation
191 Holiday Homes
Lowest Price
AU$229
Highest Price
AU$262
Popular accommodation
Quaint Southwest Mesilla Home - Pet Friendly, Desert Pool Oasis located in the heart of Las Cruces, Unique 1-bedroom casita in Mesilla Park with hot tub, Hacienda de Horacio a 3 bedroom w/2 king beds, private patio and parking. , Casita Azul, Mesilla Plaza Only Steps Away, Casa Elena Adobe casita in historic Mesilla, The Francisco and Maria Amador house is in the heart of downtown Las Cruces., 4 Bedroom Contemporary Model Home, ⭐️ Western Style Casita w/ 3BR and a Fitness Room plus View to the Mountains

Top trending hotels in Mesilla

Casita Azul, Mesilla Plaza Only Steps Away

Casita Azul, Mesilla Plaza Only Steps Away

Mesilla
With a stay at this vacation home in Mesilla, you'll be on a lake, within a 15-minute drive of New Mexico State University and Mesillia Plaza.
Casita Azul, Mesilla Plaza Only Steps Away
Josefina's King Suite in Historic Old Mesilla Plaza.

Josefina's King Suite in Historic Old Mesilla Plaza.

2 out of 5
Mesilla
The price is AU$262 per night from 5 Aug to 6 Aug
AU$262
5 Aug - 6 Aug
includes taxes & fees
With a stay at this apartment in Mesilla, you'll be within a 5-minute drive of New Mexico State University and San Albino Basilica.
Josefina's King Suite in Historic Old Mesilla Plaza.
Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces

3.5 out of 5
705 S Telshor Blvd, Las Cruces, NM
Fully refundableReserve now, pay when you stay
The price is AU$229 per night from 24 Aug to 25 Aug
AU$229
24 Aug - 25 Aug
includes taxes & fees
With a stay at Hotel Encanto de Las Cruces in Las Cruces, you'll be within a 5-minute drive of New Mexico State University and Mesilla Valley Mall.
Hotel Encanto de Las Cruces
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Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces

3 out of 5
201 E University Avenue, I-10 Exit 142, Las Cruces, NM
Located in Las Cruces, Ramada Hotel & Conference Center by Wyndham Las Cruces is just steps from New Mexico State University and a 3-minute drive from Fountain ...
Ramada Hotel & Conference Center by Wyndham Las Cruces
Don't see what you're looking for?
See all available properties in Mesilla
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.