Book Holiday Homes in Isernia

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Featured Holiday Homes in Isernia

Snow White Chalet. In the heart of the national park of abruzzo, lazio and molise.

Snow White Chalet. In the heart of the national park of abruzzo, lazio and molise.

Picinisco Frosinone
Located in Picinisco, this vacation home is within a 15-minute drive of Chiesa di San Lorenzo and Cantina La Ferriera.
Opens in a new windowSnow White Chalet. In the heart of the national park of abruzzo, lazio and molise.
Nonno Ludovico, casa vacanza

Nonno Ludovico, casa vacanza

Roccasicura Provincia di Isernia
With a stay at this vacation home, you'll be centrally located in Roccasicura, within a 15-minute drive of Montedimezzo Natural reserve and Pescolanciano-Chiauci ...
Opens in a new windowNonno Ludovico, casa vacanza
Detached house in ancient medieval village.

Detached house in ancient medieval village.

Santa Maria Oliveto Provincia di Isernia
With a stay at this vacation home in Pozzilli, you'll be within a 15-minute drive of Pandone Castle National Museum and Le Mortine Oasis.
Opens in a new windowDetached house in ancient medieval village.
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House in the mountains

House in the mountains

Colle Giovenchi Provincia dell'Aquila
Located in Ateleta, this vacation home is in the mountains, a 1-minute drive from Majella National Park and 6 minutes from Museum of Rural Culture.
Opens in a new windowHouse in the mountains
Colonial house Ciociara

Colonial house Ciociara

Cervaro Lazio
The price is AU$104 per night from 26 Dec to 27 Dec
AU$104
26 Dec - 27 Dec
includes taxes & fees
With a stay at this vacation home in Cervaro, you'll be within a 10-minute drive of Terme Varroniane and Museo Historiale.
Opens in a new windowColonial house Ciociara
La baita di Serena

La baita di Serena

Via Belvedere 7 Roccaraso AQ
When you stay at this vacation home in Roccaraso, you'll be near ski lifts and steps from Majella National Park.
Opens in a new windowLa baita di Serena
Lake view house

Lake view house

Civitella Alfedena Provincia dell'Aquila
With a stay at this vacation home in Civitella Alfedena, you'll be just steps from National Park of Abruzzo and Fondillo Valley.
Opens in a new windowLake view house
Jenny's House 5 minutes from the A1 Caianello exit.

Jenny's House 5 minutes from the A1 Caianello exit.

Campania Provincia di Caserta
The price is AU$140 per night from 26 Dec to 27 Dec
AU$140
26 Dec - 27 Dec
includes taxes & fees
Located in Marzano Appio, this vacation home is within a 15-minute drive of The Devil's Footprints and MINI AUTODROMO ROAD RACE.
Opens in a new windowJenny's House 5 minutes from the A1 Caianello exit.
Cassino-two-room apartment-park rondo

Cassino-two-room apartment-park rondo

Cassino Provincia di Frosinone
The price is AU$256 per night from 21 Jan to 22 Jan
AU$256
21 Jan - 22 Jan 2026
includes taxes & fees
With a stay at this vacation home in Cassino, you'll be within a 5-minute drive of Museo Historiale and Terme Varroniane.
Opens in a new windowCassino-two-room apartment-park rondo
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isernia Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Isernia vacation homes are the perfect way for you to wing it.

Holiday houses in Isernia let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Isernia in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Isernia adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Isernia with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Isernia vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Isernia Holiday Homes essential information

Accommodation
62 Holiday Homes
Lowest Price
AU$104
Highest Price
AU$256
Popular accommodation
Snow White Chalet. In the heart of the national park of abruzzo, lazio and molise., Nonno Ludovico, casa vacanza, Detached house in ancient medieval village., House in the mountains, Colonial house Ciociara, La baita di Serena, Lake view house, Jenny's House 5 minutes from the A1 Caianello exit., Cassino-two-room apartment-park rondo

Top trending hotels in Isernia

Central Isernia

Central Isernia

Via XXIV Maggio n. 235 Isernia IS
The price is AU$123 per night from 29 Dec to 30 Dec
AU$123
29 Dec - 30 Dec
includes taxes & fees
With a stay at Central Isernia in Isernia, you'll be within a 5-minute drive of Fontana Fraterna and Cathedral of Isernia.
Opens in a new windowCentral Isernia
Il Piccolo Principe

Il Piccolo Principe

Viale dei Pentri, 187 Isernia IS
With a stay at Il Piccolo Principe in Isernia, you'll be within a 5-minute drive of Fontana Fraterna and National Museum of the Paleolithic.
Opens in a new windowIl Piccolo Principe
Hotel Villa Danilo

Hotel Villa Danilo

3 out of 5
Contrada Stazione 1 Gamberale CH
The price is AU$156 per night from 13 Jan to 14 Jan
AU$156
13 Jan - 14 Jan 2026
includes taxes & fees
With a stay at Hotel Villa Danilo in Gamberale, you'll be 26.6 mi (42.8 km) from Roccaraso-Aremogna Ski Resort and 10 mi (16.1 km) from Majella National ...
Opens in a new windowHotel Villa Danilo
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La Fonte dell'Astore

La Fonte dell'Astore

4 out of 5
Via Santuario 15 A Castelpetroso IS
Located in Castelpetroso, La Fonte dell'Astore is within a 15-minute drive of Basilica Minore dell'Addolorata and National Museum of the Paleolithic.
Opens in a new windowLa Fonte dell'Astore
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.