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Compare hotels in Guadalupe County from AU$108

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Explore these top cities in Guadalupe County

Top trending hotels in Guadalupe County

Days Inn & Suites by Wyndham Santa Rosa

Days Inn & Suites by Wyndham Santa Rosa

2 out of 5
2255 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is AU$152 per night from 4 Jan to 5 Jan
AU$152
4 Jan - 5 Jan 2026
includes taxes & fees
Located in Santa Rosa, Days Inn & Suites by Wyndham Santa Rosa is on a lake, within a 5-minute drive of Route 66 Auto Museum and Moise Memorial Library.
Opens in a new windowDays Inn & Suites by Wyndham Santa Rosa
La Quinta Inn & Suites by Wyndham Santa Rosa

La Quinta Inn & Suites by Wyndham Santa Rosa

3 out of 5
2277 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is AU$243 per night from 28 Dec to 29 Dec
AU$243
28 Dec - 29 Dec
includes taxes & fees
With a stay at La Quinta Inn & Suites by Wyndham Santa Rosa in Santa Rosa, you'll be within a 5-minute drive of Route 66 Auto Museum and Moise Memorial ...
Opens in a new windowLa Quinta Inn & Suites by Wyndham Santa Rosa
Super 8 by Wyndham Santa Rosa

Super 8 by Wyndham Santa Rosa

2 out of 5
2075 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is AU$118 per night from 4 Jan to 5 Jan
AU$118
4 Jan - 5 Jan 2026
includes taxes & fees
Located in Santa Rosa, Super 8 by Wyndham Santa Rosa is within a 15-minute walk of Moise Memorial Library and St. Rose of Lima Catholic Church.
Opens in a new windowSuper 8 by Wyndham Santa Rosa
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Comfort Inn Santa Rosa on Route 66

Comfort Inn Santa Rosa on Route 66

2.5 out of 5
2524 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is AU$186 per night from 18 Jan to 19 Jan
AU$186
18 Jan - 19 Jan 2026
includes taxes & fees
With a stay at Comfort Inn Santa Rosa on Route 66 in Santa Rosa, you'll be within a 5-minute drive of Route 66 Auto Museum and St. Rose of Lima Catholic ...
Opens in a new windowComfort Inn Santa Rosa on Route 66
Hotel Blue 66, BW Signature Collection

Hotel Blue 66, BW Signature Collection

2.5 out of 5
2533 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is AU$158 per night from 2 Jan to 3 Jan
AU$158
2 Jan - 3 Jan 2026
includes taxes & fees
A stay at Hotel Blue 66, BW Signature Collection places you in the heart of Santa Rosa, within a 5-minute drive of Route 66 Auto Museum and St. Rose of Lima ...
Opens in a new windowHotel Blue 66, BW Signature Collection
Hampton Inn Santa Rosa

Hampton Inn Santa Rosa

2.5 out of 5
2475 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is AU$193 per night from 4 Jan to 5 Jan
AU$193
4 Jan - 5 Jan 2026
includes taxes & fees
With a stay at Hampton Inn Santa Rosa in Santa Rosa, you'll be a 3-minute walk from Route 66 Auto Museum and within a 5-minute drive of Santa Rosa Golf ...
Opens in a new windowHampton Inn Santa Rosa
Best Western Santa Rosa Inn

Best Western Santa Rosa Inn

2.5 out of 5
2491 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is AU$238 per night from 3 Jan to 4 Jan
AU$238
3 Jan - 4 Jan 2026
includes taxes & fees
Located in Santa Rosa, Best Western Santa Rosa Inn is within a 5-minute drive of Route 66 Auto Museum and Santa Rosa Golf Course.
Opens in a new windowBest Western Santa Rosa Inn
Econo Lodge

Econo Lodge

2 out of 5
2295 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is AU$135 per night from 26 Jan to 27 Jan
AU$135
26 Jan - 27 Jan 2026
includes taxes & fees
When you stay at Econo Lodge Inn & Suites Santa Rosa in Santa Rosa, you'll be next to a golf course, within a 5-minute drive of Route 66 Auto Museum and Moise ...
Opens in a new windowEcono Lodge
Motel 6 Santa Rosa, NM

Motel 6 Santa Rosa, NM

2 out of 5
3400 Will Rogers Dr Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is AU$108 per night from 1 Jan to 2 Jan
AU$108
1 Jan - 2 Jan 2026
includes taxes & fees
Located in Santa Rosa, Motel 6 Santa Rosa, NM is within a 5-minute drive of Route 66 Auto Museum and Santa Rosa Golf Course.
Opens in a new windowMotel 6 Santa Rosa, NM
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.

Guadalupe County hotels essential information

Accommodation
24 hotels
Lowest Price
AU$108
Highest Price
AU$243
Popular hotels
Days Inn & Suites by Wyndham Santa Rosa, La Quinta Inn & Suites by Wyndham Santa Rosa, Super 8 by Wyndham Santa Rosa, Comfort Inn Santa Rosa on Route 66, Hotel Blue 66, BW Signature Collection, Hampton Inn Santa Rosa, Best Western Santa Rosa Inn, Econo Lodge, Motel 6 Santa Rosa, NM

Most recent Guadalupe County hotel reviews

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.

Hotel Deals In Guadalupe County

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