Book Holiday Homes in St. Charles

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Featured Holiday Homes in St. Charles

House of Elegance Vacation Home

House of Elegance Vacation Home

St. Louis
Located in St. Louis (University City), this vacation home is within a 10-minute drive of St. Louis Zoo and Forest Park.
House of Elegance Vacation Home
St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!

St Charles
With a stay at this vacation home in St. Charles (St. Charles Historic District), you'll be a 3-minute drive from Ameristar Casino St. Charles and 6 minutes ...
St. Charles 1860's Gem - Sleeps 6!
Funky mini loft in fox park! Pet friendly!!

Funky mini loft in fox park! Pet friendly!!

St. Louis
With a stay at this vacation home in St. Louis (Fox Park), you'll be within a 5-minute drive of St. Louis Union Station and Enterprise Center.
Funky mini loft in fox park! Pet friendly!!
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Downtown St. Charles • Cozy Historic Home

Downtown St. Charles • Cozy Historic Home

Saint Charles
With a stay at this vacation home, you'll be centrally located in St. Charles, within a 10-minute drive of Ameristar Casino St. Charles and Hollywood Casino ...
Downtown St. Charles • Cozy Historic Home
beautiful small house

beautiful small house

St. Louis
With a stay at this vacation home in St. Louis (Dogtown), you'll be within a 5-minute drive of St. Louis Zoo and Forest Park.
beautiful small house
Stunning 1890's Home - Sleeps 8!

Stunning 1890's Home - Sleeps 8!

Saint Charles
With a stay at this vacation home in St. Charles (St. Charles Historic District), you'll be a 2-minute drive from Ameristar Casino St. Charles and 5 minutes ...
Stunning 1890's Home - Sleeps 8!
Tamm Ave 3-BR Retreat

Tamm Ave 3-BR Retreat

St. Louis
With a stay at this vacation home in St. Louis (Dogtown), you'll be within a 5-minute drive of St. Louis Zoo and Forest Park.
Tamm Ave 3-BR Retreat
Dogtown: St. Louis Family Favorite! Forest Park, Zoo, Arch, WashU, SLU, BJC,Yard

Dogtown: St. Louis Family Favorite! Forest Park, Zoo, Arch, WashU, SLU, BJC,Yard

St. Louis
With a stay at this vacation home in St. Louis (Dogtown), you'll be within a 5-minute drive of St. Louis Zoo and Forest Park.
Dogtown: St. Louis Family Favorite! Forest Park, Zoo, Arch, WashU, SLU, BJC,Yard
AK's STL Pearl Grey House - Game Room

AK's STL Pearl Grey House - Game Room

Maryland Heights
Located in Maryland Heights, this vacation home is within a 15-minute drive of Westport Plaza and Hollywood Casino Amphitheatre.
AK's STL Pearl Grey House - Game Room
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Charles Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our St. Charles vacation homes are the perfect way for you to wing it.

Holiday houses in St. Charles let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of St. Charles in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local St. Charles adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in St. Charles with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of St. Charles vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

St. Charles Holiday Homes essential information

Accommodation
778 Holiday Homes
Lowest Price
Highest Price
Popular accommodation
House of Elegance Vacation Home, St. Charles 1860's Gem - Sleeps 6!, Funky mini loft in fox park! Pet friendly!!, Downtown St. Charles • Cozy Historic Home, beautiful small house, Stunning 1890's Home - Sleeps 8! , Tamm Ave 3-BR Retreat, Dogtown: St. Louis Family Favorite! Forest Park, Zoo, Arch, WashU, SLU, BJC,Yard, AK's STL Pearl Grey House - Game Room

Top trending hotels in St. Charles

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
Fully refundableReserve now, pay when you stay
A stay at Ameristar Casino Resort and Spa places you in the heart of St. Charles, steps from Ameristar Casino St. Charles and a 4-minute drive from Family ...
Ameristar Casino Resort and Spa
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive, St. Charles, MO
Fully refundableReserve now, pay when you stay
When you stay at Drury Plaza Hotel St. Louis St. Charles in St. Charles, you'll be in the business district, within a 5-minute drive of Ameristar Casino St. ...
Drury Plaza Hotel St. Louis St. Charles
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St, St. Charles, MO
Fully refundable
With a stay at Country Inn & Suites by Radisson, St. Charles Historic District in St. Charles (St. Charles Historic District), you'll be a 1-minute drive from ...
Country Inn & Suites by Radisson, St. Charles Historic District
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Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
A stay at Hyatt Regency St. Louis at The Arch places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Busch Stadium.
Hyatt Regency St. Louis at The Arch
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.