Book Santiago Sur hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Santiago Sur

Cheap Santiago Sur hotels

Cabañas Palma Real

Cabañas Palma Real

3 out of 5
Las Colomas, Santiago Sur via principal, 68035902, Santiago Sur, Provincia de Veraguas
With a stay at Cabañas Palma Real in Santiago Sur, you'll be 14.6 mi (23.5 km) from Mariato Beach and 22 mi (35.5 km) from Torio Beach.
Cabañas Palma Real
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
A stay at Hotel Mykonos Panama places you in the heart of Nuevo Santiago, within a 5-minute drive of Plaza Banconal and Parque Nacional Cerro Hoya.
Hotel Mykonos Panama
Bambuda Santa Catalina

Bambuda Santa Catalina

2.5 out of 5
Finca 464377, Hicaco, Veraguas
Fully refundableReserve now, pay when you stay
When you stay at Bambuda Santa Catalina in Santa Catalina, you'll be near the beach, within a 5-minute drive of Estero Beach and Santa Catalina Island.
Bambuda Santa Catalina
Save an average of 15% on thousands of hotels when you're signed in
Hotel Galería

Hotel Galería

3 out of 5
Vía Interamericana Santiago, Km 232.88, Nuevo Santiago
Fully refundableReserve now, pay when you stay
With a stay at Hotel Galería in Nuevo Santiago, you'll be within a 5-minute drive of Plaza Banconal and Parque Nacional Cerro Hoya.
Hotel Galería
Catalina's Hideaway

Catalina's Hideaway

4 out of 5
Lagartero Beach, Hicaco, Veraguas
Located in Santa Catalina, Catalina's Hideaway is by the ocean, within a 15-minute drive of Lagartero Beach and Santa Catalina Island.
Catalina's Hideaway
Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
Located in Santiago, Hotel Gran David is in a rural location, within a 15-minute walk of Plaza Banconal and Omar Torrijos Herrera Stadium.
Hotel Gran David
Hotel y Restaurante Mama Ines

Hotel y Restaurante Mama Ines

3 out of 5
Calle Hacia Playa Estero, Hicaco, Veraguas Province
Fully refundableReserve now, pay when you stay
When you stay at Hotel y Restaurante Mama Ines in Santa Catalina, you'll be on the beach and within a 5-minute drive of Santa Catalina Island.
Hotel y Restaurante Mama Ines
Villa Coco

Villa Coco

2.5 out of 5
Via Catalina Farms, Hicaco, Veraguas
When you stay at Villa Coco in Santa Catalina, you'll be near the beach and within a 5-minute drive of Santa Catalina Island.
Villa Coco
Hotel Santa Catalina Panama

Hotel Santa Catalina Panama

3 out of 5
Calle hacia el Estero, Hicaco, Veraguas
When you stay at Hotel Santa Catalina Panama in Santa Catalina, you'll be by the ocean, within a 5-minute drive of Estero Beach and Santa Catalina Island.
Hotel Santa Catalina Panama
Don't see what you're looking for?
See all available properties in Santiago Sur
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.

Santiago Sur hotels essential information

Accommodation
54 hotels
Lowest Price
Highest Price
Popular hotels
Cabañas Palma Real, Hotel Mykonos Panama, Bambuda Santa Catalina, Hotel Galería, Catalina's Hideaway, Hotel Gran David, Hotel y Restaurante Mama Ines, Villa Coco, Hotel Santa Catalina Panama

Most recent Santiago Sur hotel reviews

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.