Book Holiday Homes in Santa Isabel

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Featured Holiday Homes in Santa Isabel

Discover the perfect retreat in nature with the best sunset in southern PR.

Discover the perfect retreat in nature with the best sunset in southern PR.

Salinas Salinas
When you stay at this vacation home in Salinas, you'll be within a 10-minute drive of Marina de Salinas and Albergue Olimpico.
Opens in a new windowDiscover the perfect retreat in nature with the best sunset in southern PR.
Camila's Getaway - Charming 2-bedroom house with WiFi, AC in Salinas

Camila's Getaway - Charming 2-bedroom house with WiFi, AC in Salinas

Salinas PR
With a stay at this vacation home in Salinas, you'll be within a 5-minute drive of Marina de Salinas and Playa La Ochenta.
Opens in a new windowCamila's Getaway - Charming 2-bedroom house with WiFi, AC in Salinas
Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony

Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony

Barranquitas Puerto Rico
The price is AU$220 per night from 2 Apr to 3 Apr
AU$220
2 Apr - 3 Apr
includes taxes & fees
A stay at this vacation home places you in the heart of Barranquitas, and within a short 3-minute drive from Finca Don Felix para la Naturaleza.
Opens in a new windowCasita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony
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*Amazing Views*Mountain top*Temp 60s F*Heated Spa*

*Amazing Views*Mountain top*Temp 60s F*Heated Spa*

Aibonito PR
The price is AU$1,302 per night from 4 Apr to 5 Apr
AU$1,302
4 Apr - 5 Apr
includes taxes & fees
Located in Aibonito, this vacation home is in the mountains, within a 15-minute drive of Mirador La Piedra Degetau and Plaza Las Flores.
Opens in a new window*Amazing Views*Mountain top*Temp 60s F*Heated Spa*
Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking

Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking

Barranquitas
When you stay at this vacation home in Barranquitas, you'll be in the mountains and within a short 4-minute drive from Finca Don Felix para la Naturaleza.
Opens in a new windowCharming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking
Casa Boni Guest House, Vista única al lago de Carite.

Casa Boni Guest House, Vista única al lago de Carite.

Guayama Guayama
When you stay at this vacation home in Guayama, you'll be on a lake and 12 minutes by car from Bosque Estatal De Carite.
Opens in a new windowCasa Boni Guest House, Vista única al lago de Carite.
Modern Cozy Home in Puerto Rican Paradise

Modern Cozy Home in Puerto Rican Paradise

Santa Isabel
With a stay at this vacation home in Santa Isabel, you'll be within a 10-minute drive of Carribbean Cinemas Santa Isabel and Playa La Ochenta.
Opens in a new windowModern Cozy Home in Puerto Rican Paradise
3-bedroom house in Coamo with AC on bedroom 1

3-bedroom house in Coamo with AC on bedroom 1

Coamo Pr
The price is AU$199 per night from 22 Mar to 23 Mar
AU$199
22 Mar - 23 Mar
includes taxes & fees
Located in Coamo, 3-bedroom house in Coamo with AC on bedroom 1 is in the mountains, within a 10-minute drive of Coamo Historical Museum and Coamo Springs.
Opens in a new window3-bedroom house in Coamo with AC on bedroom 1
The charming 11 minutes from the baths of Coamo. To feel at home!!!

The charming 11 minutes from the baths of Coamo. To feel at home!!!

Mariano Colon Coamo
With a stay at this vacation home in Coamo, you'll be within a 10-minute drive of Coamo Springs and Playa La Ochenta.
Opens in a new windowThe charming 11 minutes from the baths of Coamo. To feel at home!!!
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Isabel Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Santa Isabel vacation homes are the perfect way for you to wing it.

Holiday houses in Santa Isabel let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Santa Isabel in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Santa Isabel adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Santa Isabel with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Santa Isabel vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Santa Isabel Holiday Homes essential information

Accommodation
106 Holiday Homes
Lowest Price
AU$199
Highest Price
AU$1,302
Popular accommodation
Discover the perfect retreat in nature with the best sunset in southern PR., Camila's Getaway - Charming 2-bedroom house with WiFi, AC in Salinas, Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony, *Amazing Views*Mountain top*Temp 60s F*Heated Spa*, Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking, Casa Boni Guest House, Vista única al lago de Carite. , Modern Cozy Home in Puerto Rican Paradise, 3-bedroom house in Coamo with AC on bedroom 1, The charming 11 minutes from the baths of Coamo. To feel at home!!!

Top trending hotels in Santa Isabel

Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9 Santa Isabel
Located in Santa Isabel, Hotel Las Vegas is a 4-minute drive from Carribbean Cinemas Santa Isabel and 10 minutes from Coamo Springs.
Opens in a new windowHotel Las Vegas
3BR Puerto Rico Villa w Pool | Aqua Bella 1

3BR Puerto Rico Villa w Pool | Aqua Bella 1

Santa Isabel PR
Located in Santa Isabel, this vacation home is by the ocean, within a 15-minute drive of Carribbean Cinemas Santa Isabel and Playa La Ochenta.
Opens in a new window3BR Puerto Rico Villa w Pool | Aqua Bella 1
Modern Cozy Home in Puerto Rican Paradise

Modern Cozy Home in Puerto Rican Paradise

Santa Isabel
With a stay at this vacation home in Santa Isabel, you'll be within a 10-minute drive of Carribbean Cinemas Santa Isabel and Playa La Ochenta.
Opens in a new windowModern Cozy Home in Puerto Rican Paradise
Save an average of 15% on thousands of hotels when you're signed in
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
The price is AU$523 per night from 2 Apr to 3 Apr
AU$523
2 Apr - 3 Apr
includes taxes & fees
Located in Santa Isabel, this vacation home is by the ocean, within a 15-minute drive of Playa La Ochenta and Marina de Salinas.
Opens in a new windowCultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Don't see what you're looking for?
See all available properties in Santa Isabel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.