Book Holiday Homes in Santa Isabel

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in Santa Isabel

Grandpa's lake house lake private access mountain view museum 1950's experience

Grandpa's lake house lake private access mountain view museum 1950's experience

Cidra
The price is AU$176 per night from 6 May to 7 May
AU$176
includes taxes & fees
6 May - 7 May
With a stay at this vacation home in Cidra, you'll be on the waterfront, and 23.4 mi (37.6 km) from Condado Beach and 23.5 mi (37.8 km) from Puerto Rico Convention ...
Grandpa's lake house lake private access mountain view museum 1950's experience
Modern Cozy Home in Puerto Rican Paradise

Modern Cozy Home in Puerto Rican Paradise

Santa Isabel
With a stay at this vacation home in Santa Isabel, you'll be within a 10-minute drive of Carribbean Cinemas Santa Isabel and Playa La Ochenta.
Modern Cozy Home in Puerto Rican Paradise
Complete Remodel House quite 2 minutes from beach Urbanizacion Vista del Sol.

Complete Remodel House quite 2 minutes from beach Urbanizacion Vista del Sol.

Guayama
Located in Guayama, this vacation home is within a 5-minute drive of Museo Casa Cautino and Carribbean Cinemas Guayama.
Complete Remodel House quite 2 minutes from beach Urbanizacion Vista del Sol.
Save an average of 15% on thousands of hotels when you're signed in
Hacienda Margarita Mountain Top Inn & Panoramic Pool in Central Puerto Rico

Hacienda Margarita Mountain Top Inn & Panoramic Pool in Central Puerto Rico

Barranquitas
When you stay at this vacation home in Barranquitas, you'll be 7 minutes by car from Finca Don Felix para la Naturaleza.
Hacienda Margarita Mountain Top Inn & Panoramic Pool in Central Puerto Rico
Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking

Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking

2 out of 5
Barranquitas
When you stay at this vacation home in Barranquitas, you'll be in the mountains and within a 5-minute drive of Finca Don Felix para la Naturaleza.
Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking
Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views.

Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views.

Barranquitas
When you stay at this vacation home in Barranquitas, you'll be 11 minutes by car from Finca Don Felix para la Naturaleza.
Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views.
*Amazing Views*Mountain top*Temp 60s F*Heated Spa*

*Amazing Views*Mountain top*Temp 60s F*Heated Spa*

Aibonito
Located in Aibonito, this vacation home is in the mountains, within a 15-minute drive of Mirador La Piedra Degetau and Plaza Las Flores.
*Amazing Views*Mountain top*Temp 60s F*Heated Spa*
Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

Cidra
The price is AU$431 per night from 16 May to 17 May
AU$431
includes taxes & fees
16 May - 17 May
With a stay at this vacation home in Cidra, you'll be 25.8 mi (41.5 km) from El Yunque National Forest and 29.4 mi (47.3 km) from Puerto Rico Convention ...
Cozy studio with private Pool and Bar modern amentities perfect for relaxation.
Casa Boni Guest House, Vista única al lago de Carite.

Casa Boni Guest House, Vista única al lago de Carite.

Guayama
When you stay at this vacation home in Guayama, you'll be on a lake and 12 minutes by car from Bosque Estatal De Carite.
Casa Boni Guest House, Vista única al lago de Carite.
Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Isabel Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Santa Isabel vacation homes are the perfect way for you to wing it.

Holiday houses in Santa Isabel let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Santa Isabel in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Santa Isabel adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Santa Isabel with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Santa Isabel vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Santa Isabel Holiday Homes essential information

Accommodation
85 Holiday Homes
Lowest Price
AU$155
Highest Price
AU$577
Popular accommodation
Grandpa's lake house lake private access mountain view museum 1950's experience, Modern Cozy Home in Puerto Rican Paradise, Complete Remodel House quite 2 minutes from beach Urbanizacion Vista del Sol., Hacienda Margarita Mountain Top Inn & Panoramic Pool in Central Puerto Rico, Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking, Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views., *Amazing Views*Mountain top*Temp 60s F*Heated Spa*, Cozy studio with private Pool and Bar modern amentities perfect for relaxation., Casa Boni Guest House, Vista única al lago de Carite.

Top trending hotels in Santa Isabel

Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9, Santa Isabel
The price is AU$155 per night from 4 May to 5 May
AU$155
includes taxes & fees
4 May - 5 May
With a stay at Hotel Las Vegas in Santa Isabel, you'll be within a 15-minute drive of Carribbean Cinemas Santa Isabel and Coamo Springs.
Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
The price is AU$345 per night from 2 Jun to 3 Jun
AU$345
includes taxes & fees
2 June - 3 June
Located in Santa Isabel, Hacienda del Sur is within a 15-minute drive of Carribbean Cinemas Santa Isabel and Coamo Springs.
Hacienda del Sur
Beachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views

Beachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views

santa isabel
Located in Santa Isabel, this villa is a 2-minute drive from Playa La Ochenta and 8 minutes from Marina de Salinas.
Beachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views
Save an average of 15% on thousands of hotels when you're signed in
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
The price is AU$577 per night from 12 May to 13 May
AU$577
includes taxes & fees
12 May - 13 May
Located in Santa Isabel, this vacation home is by the ocean, within a 15-minute drive of Playa La Ochenta and Marina de Salinas.
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.