Book Holiday Homes in Santa Isabel

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in Santa Isabel

Grandpa's lake house lake private access mountain view museum 1950's experience

Grandpa's lake house lake private access mountain view museum 1950's experience

Cidra
Located in Cidra, this vacation home is on the waterfront, within a 15-minute drive of Carribbean Cinemas Cayey and Jardin Botanico y Cultural de Caguas.
Grandpa's lake house lake private access mountain view museum 1950's experience
Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking

Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking

2 out of 5
Barranquitas
When you stay at this vacation home in Barranquitas, you'll be in the mountains and within a 5-minute drive of Finca Don Felix para la Naturaleza.
Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking
A cozy place to stay walking distance from the beach and Restaurants.

A cozy place to stay walking distance from the beach and Restaurants.

Salinas
When you stay at this vacation home in Salinas, you'll be on the beach, within a 5-minute drive of Marina de Salinas and Playa La Ochenta.
A cozy place to stay walking distance from the beach and Restaurants.
Save an average of 15% on thousands of hotels when you're signed in
Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views.

Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views.

Barranquitas
When you stay at this vacation home in Barranquitas, you'll be 11 minutes by car from Finca Don Felix para la Naturaleza.
Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views.
Big House in Salinas by the Beach, Relaxing, & Family Friendly!

Big House in Salinas by the Beach, Relaxing, & Family Friendly!

Salinas
When you stay at this vacation home in Salinas, you'll be by the sea, within a 5-minute drive of Marina de Salinas and Playa La Ochenta.
Big House in Salinas by the Beach, Relaxing, & Family Friendly!
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
Located in Santa Isabel, this vacation home is by the ocean, within a 15-minute drive of Playa La Ochenta and Marina de Salinas.
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Heavenly Retreat in the Mountains of Ciales | Incredible Views Stretching to the San Juan Coastline

Heavenly Retreat in the Mountains of Ciales | Incredible Views Stretching to the San Juan Coastline

Ciales
With a stay at this vacation home in Ciales, you'll be in the mountains, and 31.9 mi (51.3 km) from Dorado Beach and 8.8 mi (14.1 km) from Chorro de Doña Juana ...
Heavenly Retreat in the Mountains of Ciales | Incredible Views Stretching to the San Juan Coastline
Oasis Salinas

Oasis Salinas

Salinas
A stay at this vacation home places you in the heart of Salinas, within a 5-minute drive of Marina de Salinas and Playa La Ochenta.
Oasis Salinas
Hacienda Pura Vida | Mountain Paradise w. Pool

Hacienda Pura Vida | Mountain Paradise w. Pool

Cayey
With a stay at this vacation home in Cayey, you'll be in the mountains, and 6 mi (9.7 km) from Albergue Olimpico and 7.5 mi (12.1 km) from Carribbean Cinemas ...
Hacienda Pura Vida | Mountain Paradise w. Pool
Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Isabel Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Santa Isabel vacation homes are the perfect way for you to wing it.

Holiday houses in Santa Isabel let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Santa Isabel in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Santa Isabel adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Santa Isabel with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Santa Isabel vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Santa Isabel Holiday Homes essential information

Accommodation
91 Holiday Homes
Lowest Price
Highest Price
Popular accommodation
Grandpa's lake house lake private access mountain view museum 1950's experience, Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking, A cozy place to stay walking distance from the beach and Restaurants., Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views., Big House in Salinas by the Beach, Relaxing, & Family Friendly!, Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep, Heavenly Retreat in the Mountains of Ciales | Incredible Views Stretching to the San Juan Coastline, Oasis Salinas , Hacienda Pura Vida | Mountain Paradise w. Pool

Top trending hotels in Santa Isabel

Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9, Santa Isabel
With a stay at Hotel Las Vegas in Santa Isabel, you'll be within a 15-minute drive of Carribbean Cinemas Santa Isabel and Coamo Springs.
Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
Located in Santa Isabel, Hacienda del Sur is within a 15-minute drive of Carribbean Cinemas Santa Isabel and Coamo Springs.
Hacienda del Sur
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
Located in Santa Isabel, this vacation home is by the ocean, within a 15-minute drive of Playa La Ochenta and Marina de Salinas.
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Save an average of 15% on thousands of hotels when you're signed in
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Santa Isabel
Located in Santa Isabel, this vacation home is in the mountains, within a 10-minute drive of Carribbean Cinemas Santa Isabel and Playa La Ochenta.
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.