Book Holiday Homes in Santa Cruz

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Featured Holiday Homes in Santa Cruz

Spacious 5-bedroom house with amenities near San Fernando, Chile

Spacious 5-bedroom house with amenities near San Fernando, Chile

San Fernando O'Higgins
With a stay at this vacation home in San Fernando, you'll be within a 5-minute walk of Plaza de San Fernando and Iglesia de San Francisco.
Opens in a new windowSpacious 5-bedroom house with amenities near San Fernando, Chile
Hostel Turismo San Vicente Tagua Tagua

Hostel Turismo San Vicente Tagua Tagua

San Vicente de Taguatagua O'Higgins
The price is AU$122 per night from 29 Dec to 30 Dec
AU$122
29 Dec - 30 Dec
With a stay at this vacation home in San Vicente, you'll be within a 5-minute drive of San Vicente Square and TreMonte Winery / Vina TreMonte.
Opens in a new windowHostel Turismo San Vicente Tagua Tagua
Los Suspiros Country House

Los Suspiros Country House

Region del libertador Bernardo O'Higgins
Located in Nancagua, this vacation home is within a 15-minute drive of Bodega Viña Viu Manent and Viña Escondida.
Opens in a new windowLos Suspiros Country House
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The ambush. Field and comfort

The ambush. Field and comfort

Santa Cruz Región del Libertador Gral. Bernardo O’Higgins
The price is AU$295 per night from 29 Dec to 30 Dec
AU$295
29 Dec - 30 Dec
Located in Santa Cruz, this vacation home is in a rural location, within a 10-minute drive of Plaza de Armas and Museo de Colchagua.
Opens in a new windowThe ambush. Field and comfort
Hosteria No me Olvides

Hosteria No me Olvides

2 out of 5
Agustin besoain 320 Curicó Maule (region)
Located in Curicó, this vacation home is a 3-minute drive from Plaza de Armas and 8 minutes from Miguel Torres Winery.
Opens in a new windowHosteria No me Olvides
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Cruz Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Santa Cruz vacation homes are the perfect way for you to wing it.

Holiday houses in Santa Cruz let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Santa Cruz in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Santa Cruz adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Santa Cruz with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Santa Cruz vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Santa Cruz Holiday Homes essential information

Accommodation
5 Holiday Homes
Lowest Price
AU$122
Highest Price
AU$295
Popular accommodation
Spacious 5-bedroom house with amenities near San Fernando, Chile, Hostel Turismo San Vicente Tagua Tagua, Los Suspiros Country House, The ambush. Field and comfort, Hosteria No me Olvides

Top trending hotels in Santa Cruz

Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is AU$194 per night from 13 Jan to 14 Jan
AU$194
13 Jan - 14 Jan 2026
A stay at Santa Cruz Plaza places you in the heart of Santa Cruz, steps from Plaza de Armas and 3 minutes by foot from Museo de Colchagua.
Opens in a new windowSanta Cruz Plaza
Hotel Cava Colchagua

Hotel Cava Colchagua

4 out of 5
Barreales´s Way Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
A stay at Hotel Cava Colchagua places you in the heart of Santa Cruz, within a 5-minute drive of Laura Hartwig Winery and Plaza de Armas.
Opens in a new windowHotel Cava Colchagua
TerraViña

TerraViña

3 out of 5
Camino Los Boldos S/n Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is AU$241 per night from 29 Dec to 30 Dec
AU$241
29 Dec - 30 Dec
Located in Santa Cruz, TerraViña is in a rural location, within a 5-minute drive of Plaza de Armas and Laura Hartwig Winery.
Opens in a new windowTerraViña
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La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía Santa Cruz O'Higgins
Located in Santa Cruz, La Perla Hotel is in the suburbs, within a 5-minute drive of Museo de Colchagua and Casino Colchagua.
Opens in a new windowLa Perla Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.