Find Santa Ana hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Santa Ana

Top trending hotels in Santa Ana

Casa Buho B&B

Casa Buho B&B

3 out of 5
77 Calle del Agua Antigua Guatemala Guatemala
The price is AU$77 per night from 1 June to 2 June
AU$77
1 June - 2 June
includes taxes & fees
With a stay at Casa Buho B&B in Antigua Guatemala (Santa Ana), you'll be within a 5-minute drive of Casa Santo Domingo Museum and Antigua Guatemala ...
Opens in a new windowCasa Buho B&B
Porta Hotel Antigua

Porta Hotel Antigua

4.5 out of 5
8va Calle Poniente No1 Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
The price is AU$279 per night from 9 June to 10 June
AU$279
9 June - 10 June
includes taxes & fees
A stay at Porta Hotel Antigua places you in the heart of Antigua Guatemala, within a 10-minute walk of Antigua Guatemala Cathedral and Central Park.
Opens in a new windowPorta Hotel Antigua
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is AU$356 per night from 18 May to 19 May
AU$356
18 May - 19 May
includes taxes & fees
A stay at Hotel Camino Real Antigua places you in the heart of Antigua Guatemala, within a 10-minute walk of Central Park and Antigua Guatemala Cathedral.
Opens in a new windowHotel Camino Real Antigua
Save an average of 15% on thousands of hotels when you're signed in
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
The price is AU$420 per night from 7 June to 8 June
AU$420
7 June - 8 June
includes taxes & fees
With a stay at Hotel Museo Spa Casa Santo Domingo in Antigua Guatemala (Barrio de La Concepción), you'll be steps from Casa Santo Domingo Museum and 8 minutes ...
Opens in a new windowHotel Museo Spa Casa Santo Domingo
Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center

4.5 out of 5
Calzada Roosevelt 22-43 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is AU$191 per night from 17 May to 18 May
AU$191
17 May - 18 May
includes taxes & fees
Located in Guatemala City (Zona 11), Tikal Futura Hotel & Convention Center is within a 5-minute drive of Museo Miraflores and Kaminaljuyu.
Opens in a new windowTikal Futura Hotel & Convention Center
Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is AU$181 per night from 14 June to 15 June
AU$181
14 June - 15 June
includes taxes & fees
Located in Guatemala City (Zona 9), Barceló Guatemala City is within a 5-minute drive of Natural History Museum and Oakland Mall.
Opens in a new windowBarceló Guatemala City
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is AU$156 per night from 31 May to 1 June
AU$156
31 May - 1 June
includes taxes & fees
With a stay at Wyndham Garden Guatemala City in Guatemala City (Zona 10), you'll be within a 15-minute walk of Embassy of Mexico in Guatemala and Oakland ...
Opens in a new windowWyndham Garden Guatemala City
Clarion Suites Guatemala City

Clarion Suites Guatemala City

4 out of 5
14 Street 3-08 Zona 10 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is AU$210 per night from 16 May to 17 May
AU$210
16 May - 17 May
includes taxes & fees
Clarion Suites Guatemala City is centrally located in Guatemala City, a 3-minute walk from Avenida La Reforma and 10 minutes by foot from Oakland Mall.
Opens in a new windowClarion Suites Guatemala City
Best Western Plus Hotel Stofella

Best Western Plus Hotel Stofella

4 out of 5
2 Avenida 12-28 Zona 10 Guatemala City Guatemala
Fully refundable
The price is AU$155 per night from 29 May to 30 May
AU$155
29 May - 30 May
includes taxes & fees
With a stay at Best Western Plus Hotel Stofella in Guatemala City (Zona 10), you'll be within a 15-minute drive of Paseo Cayala and U.S. Embassy in ...
Opens in a new windowBest Western Plus Hotel Stofella
Don't see what you're looking for?
See all available properties in Santa Ana
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Ana Hotels

Haven’t you been dying to check out that swanky new coffee shop? What about the recently opened bar serving drinks in mason jars? And let’s not forget about the barber shops willing to give you a shaved-on-the-sides, long-on-top cut whenever you want. Don’t worry; we’ll help you find the best deals at hotels in Santa Ana.

This hip new ’hood will charm the-you-know-what off you. Santa Ana hotels are comfortable and affordable, and many offer amenities like room service for those late-night meals, as well as a pool to swim in. Some of these hotels will also have you near great shopping such as souvenir shops, clothing boutiques and everything in between. Don’t feel like leaving the hotel for dinner and drinks? Hang out in the lobby bar and meet some of your fellow travellers—you never what kinds of stories they have in their memory log.

There’s no point in going somewhere if you’re not going to stay where all the action is. lastminute.com.au gets you the best offers on where to stay in Santa Ana so you don’t have to waste endless hours searching online. The trip of a lifetime is at your fingertips. Click and go!

Santa Ana hotels essential information

Accommodation
1,241 hotels
Lowest Price
AU$77
Highest Price
AU$420
Popular hotels
Casa Buho B&B, Barceló Guatemala City, Tikal Futura Hotel & Convention Center, Clarion Suites Guatemala City, Hotel Museo Spa Casa Santo Domingo, Hotel Camino Real Antigua, Best Western Plus Hotel Stofella, Porta Hotel Antigua, Wyndham Garden Guatemala City

Most recent Santa Ana hotel reviews