Book Holiday Homes in Mayo

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Featured Holiday Homes in Mayo

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

Fort White,
When you a stay at this vacation home in Fort White, you'll be on a river, just steps from Ichetucknee Springs State Park and Ichetucknee River.
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River
Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock

Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock

Branford
When you a stay at this vacation home in Branford, you'll be on the waterfront, just steps from Santa Fe River and Fort White Wildlife and Environmental ...
Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock
Scallop and Fishing Paradise

Scallop and Fishing Paradise

Steinhatchee
Located in Steinhatchee, this vacation home is within a 15-minute walk of Steinhatchee Public Boat Ramp and Sea Hag Marina.
Scallop and Fishing Paradise
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3-bedroom house in charming Steinhatchee with AC, WiFi. Enjoy a relaxing getaway

3-bedroom house in charming Steinhatchee with AC, WiFi. Enjoy a relaxing getaway

Steinhatchee
Located in Steinhatchee, this vacation home is within a 5-minute drive of Fort Steinhatchee Pier and Sea Hag Marina.
3-bedroom house in charming Steinhatchee with AC, WiFi. Enjoy a relaxing getaway
Escape to Serenity at Suwannee River Rest – Pet-Friendly Lodge in North Florida

Escape to Serenity at Suwannee River Rest – Pet-Friendly Lodge in North Florida

Branford
When you a stay at this vacation home in Branford, you'll be on the waterfront, just steps from Suwannee River and Stuarts Landing Conservation Area.
Escape to Serenity at Suwannee River Rest – Pet-Friendly Lodge in North Florida
House and dock are completely remodeled and ready for guest.

House and dock are completely remodeled and ready for guest.

Steinhatchee
With a stay at this vacation home in Steinhatchee, you'll be on the waterfront, just a 1-minute walk from Sea Hag Marina and 6 minutes by foot from Steinhatchee ...
House and dock are completely remodeled and ready for guest.
New riverfront home across from Rock Bluff Springs on the Suwannee river

New riverfront home across from Rock Bluff Springs on the Suwannee river

Branford
Located in Old Town, this vacation home is on the waterfront, within a 5-minute walk of Suwannee River and Bob's River Place.
New riverfront home across from Rock Bluff Springs on the Suwannee river
The Hatch House

The Hatch House

Steinhatchee
Located in Steinhatchee, this vacation home is on the waterfront, within a 5-minute drive of Fort Steinhatchee Pier and Sea Hag Marina.
The Hatch House
Peaceful cabin w/fireplace and hot tub, 10 minutes from the springs!

Peaceful cabin w/fireplace and hot tub, 10 minutes from the springs!

Fort White
When you stay at this vacation home in Fort White, you'll be on a river, within a 5-minute drive of Santa Fe River and Fort White Library.
Peaceful cabin w/fireplace and hot tub, 10 minutes from the springs!
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mayo Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Mayo vacation homes are the perfect way for you to wing it.

Holiday houses in Mayo let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Mayo in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Mayo adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Mayo with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Mayo vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Mayo Holiday Homes essential information

Accommodation
192 Holiday Homes
Lowest Price
Highest Price
Popular accommodation
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River, Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock, Scallop and Fishing Paradise, 3-bedroom house in charming Steinhatchee with AC, WiFi. Enjoy a relaxing getaway, Escape to Serenity at Suwannee River Rest – Pet-Friendly Lodge in North Florida, House and dock are completely remodeled and ready for guest., New riverfront home across from Rock Bluff Springs on the Suwannee river, The Hatch House, Peaceful cabin w/fireplace and hot tub, 10 minutes from the springs!

Top trending hotels in Mayo

Suwannee River Rendezvous

Suwannee River Rendezvous

2.5 out of 5
828 NE Primrose Rd, Mayo, FL
Fully refundableReserve now, pay when you stay
Located in Mayo, Suwannee River Rendezvous is within a 15-minute drive of Suwannee River and Lafayette County Library.
Suwannee River Rendezvous
Cindys Motel

Cindys Motel

2.5 out of 5
487 W Main St, Mayo, FL
Fully refundableReserve now, pay when you stay
With a stay at Cindys Motel in Mayo, you'll be a 3-minute walk from Veteran's Memorial Park of Mayo and 8 minutes by foot from Lafayette County Library.
Cindys Motel
The River House

The River House

Mayo
Located in Mayo, this vacation home is on the waterfront, within a 15-minute drive of Suwannee River and Lafayette County Library.
The River House
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Holiday Inn Express Hotel & Suites LIVE OAK by IHG

Holiday Inn Express Hotel & Suites LIVE OAK by IHG

2.5 out of 5
6694 Us Highway 129, Live Oak, FL
Fully refundable
Located in Live Oak, Holiday Inn Express Hotel & Suites LIVE OAK by IHG is in a rural location, a 4-minute drive from Suwannee County Historical Museum and 6 ...
Holiday Inn Express Hotel & Suites LIVE OAK by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.