Book Holiday Homes in Los Santos

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in Los Santos

Beachfront Villa in Decameron

Beachfront Villa in Decameron

Río Hato
The price is AU$388 per night from 19 Aug to 20 Aug
AU$388
19 Aug - 20 Aug
includes taxes & fees
Located in Rio Hato, this vacation home is within a 15-minute drive of Playa Blanca and Farallón Beach.
Beachfront Villa in Decameron
Santa Monica Beach House. 10 minutes from the beach! Pacific Riviera of Panama.

Santa Monica Beach House. 10 minutes from the beach! Pacific Riviera of Panama.

El Chirú
When you stay at this vacation home in El Chiru, you'll be close to Parroquia Santiago Apóstol de Río Hato.
Santa Monica Beach House. 10 minutes from the beach! Pacific Riviera of Panama.
GoldSky Hacienda with pool

GoldSky Hacienda with pool

Rio Hato
When you stay at this vacation home in Rio Hato, you'll be next to a golf course, within a 15-minute drive of Playa Blanca and Farallón Beach.
GoldSky Hacienda with pool
Save an average of 15% on thousands of hotels when you're signed in
Beach House / 6 People / Pool / Pet Friendly / Tourist Area

Beach House / 6 People / Pool / Pet Friendly / Tourist Area

Río Hato
With a stay at this vacation home, you'll be centrally located in Rio Hato, a 3-minute drive from Playa Blanca and 7 minutes from Parroquia Santiago Apóstol ...
Beach House / 6 People / Pool / Pet Friendly / Tourist Area
Santa Clara ocean front beach house… from your lawn right onto the sand.

Santa Clara ocean front beach house… from your lawn right onto the sand.

Santa Clara
With a stay at this vacation home in Rio Hato, you'll be within a 15-minute drive of Playa Blanca and Santa Clara Beach.
Santa Clara ocean front beach house… from your lawn right onto the sand.
Marina garden bbq private pool

Marina garden bbq private pool

2 out of 5
Rio Hato
With a stay at this vacation home in El Chiru, you'll be within a 10-minute drive of Playa Blanca and Buenaventura Marina.
Marina garden bbq private pool
Beautiful Beach House and Casita at Playa Uverito, Las Tablas Panama

Beautiful Beach House and Casita at Playa Uverito, Las Tablas Panama

Las Tablas
Located in Las Tablas, this vacation home is by the sea, a 2-minute drive from El Uverito Beach and 10 minutes from Cerro La Teta.
Beautiful Beach House and Casita at Playa Uverito, Las Tablas Panama
Residence 51 - Blue Venao
A luxury 4 bedroom 4.5 bathroom beachfront residence

Residence 51 - Blue Venao A luxury 4 bedroom 4.5 bathroom beachfront residence

Playa Venao
With a stay at this vacation home in Las Escobas del Venado, you'll be on the beach and 6 minutes by foot from Venao Beach.
Residence 51 - Blue Venao A luxury 4 bedroom 4.5 bathroom beachfront residence
Amazing House in Pedasi with Pool and Beautiful Views

Amazing House in Pedasi with Pool and Beautiful Views

pedasi
Located in Pedasí, this vacation home is by the ocean, within a 15-minute drive of Playa El Toro and Playa El Arenal.
Amazing House in Pedasi with Pool and Beautiful Views
Don't see what you're looking for?
See all available properties in Los Santos
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Los Santos Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Los Santos vacation homes are the perfect way for you to wing it.

Holiday houses in Los Santos let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Los Santos in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Los Santos adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Los Santos with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Los Santos vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Los Santos Holiday Homes essential information

Accommodation
71 Holiday Homes
Lowest Price
AU$135
Highest Price
AU$388
Popular accommodation
Beachfront Villa in Decameron, Santa Monica Beach House. 10 minutes from the beach! Pacific Riviera of Panama., GoldSky Hacienda with pool, Beach House / 6 People / Pool / Pet Friendly / Tourist Area, Santa Clara ocean front beach house… from your lawn right onto the sand., Marina garden bbq private pool , Beautiful Beach House and Casita at Playa Uverito, Las Tablas Panama, Residence 51 - Blue Venao A luxury 4 bedroom 4.5 bathroom beachfront residence, Amazing House in Pedasi with Pool and Beautiful Views

Top trending hotels in Los Santos

Villa Marina Lodge & Condos

Villa Marina Lodge & Condos

3.5 out of 5
Playa Venao, Las Escobas del Venado, Los Santos
Fully refundableReserve now, pay when you stay
The price is AU$293 per night from 1 Sept to 2 Sept
AU$293
1 Sept - 2 Sept
includes taxes & fees
When you stay at Villa Marina Lodge & Condos in Las Escobas del Venado, you'll be on the beach and 7 minutes by car from Venao Beach.
Villa Marina Lodge & Condos
Hotel Presidente

Hotel Presidente

3.5 out of 5
Calle Moises Espino, y Calle Pablo Arosemena, Las Tablas
The price is AU$135 per night from 21 Aug to 22 Aug
AU$135
21 Aug - 22 Aug
includes taxes & fees
With a stay at Hotel Presidente in Las Tablas, you'll be just steps from Belisario Porras Park and Iglesia Santa Librada.
Hotel Presidente
Hotel Posada Destiladeros

Hotel Posada Destiladeros

3 out of 5
Calle principal Los Destiladeros, Los Destiladeros Pedasi, Punta Mala, Provincia de los Santos
Fully refundableReserve now, pay when you stay
The price is AU$152 per night from 26 Aug to 27 Aug
AU$152
26 Aug - 27 Aug
includes taxes & fees
With a stay at Hotel Posada Destiladeros in Punta Mala, you'll be 0.1 mi (0.1 km) from Los Destiladeros Beach and 7.9 mi (12.7 km) from Playa El Toro.
Hotel Posada Destiladeros
Save an average of 15% on thousands of hotels when you're signed in
Pocri Country Resort

Pocri Country Resort

3 out of 5
El Llano, Calle Villa Del Carmen, Pocrí, Provincia de Los Santos
The price is AU$185 per night from 21 Aug to 22 Aug
AU$185
21 Aug - 22 Aug
includes taxes & fees
When you stay at Pocri Country Resort in Pocrí, you'll be within a 5-minute drive of Isla de Cañas.
Pocri Country Resort
Don't see what you're looking for?
See all available properties in Los Santos
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More ways to explore Los Santos

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.