Book Holiday Homes in Isla Grande

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Featured Holiday Homes in Isla Grande

Spacious Beach House on the ocean front with huge pool and patio.

Spacious Beach House on the ocean front with huge pool and patio.

Republic de Panama - Guanche - Colon - P
Located in Mechi, this vacation home is by the ocean, a 4-minute drive from Playa La Angosta and 8 minutes from Portobelo National Park.
Opens in a new windowSpacious Beach House on the ocean front with huge pool and patio.
Cabaña La Punta op het Strand!!

Cabaña La Punta op het Strand!!

Colón Province
The price is AU$266 per night from 28 Sept to 29 Sept
AU$266
28 Sept - 29 Sept
includes taxes & fees
This vacation home is within the vicinity of Isla Mamey and Portobelo National Park.
Opens in a new windowCabaña La Punta op het Strand!!
Casa Dinis - Casa Grande - Centro DE Portobelo

Casa Dinis - Casa Grande - Centro DE Portobelo

Portobelo
The price is AU$919 per night from 28 Sept to 29 Sept
AU$919
28 Sept - 29 Sept
includes taxes & fees
With a stay at this vacation home in Portobelo, you'll be just steps from Real Aduana de Portobelo and Fuerte San Jerónimo.
Opens in a new windowCasa Dinis - Casa Grande - Centro DE Portobelo
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A fantastic place between the sea and the jungle

A fantastic place between the sea and the jungle

Colon
This beach vacation home is 6.9 mi (11.1 km) from Isla Mamey and 9.6 mi (15.4 km) from Blanca Beach.
Opens in a new windowA fantastic place between the sea and the jungle
Caribbean Paradise - Beachfront Getaway

Caribbean Paradise - Beachfront Getaway

Palenque
The price is AU$759 per night from 28 Sept to 29 Sept
AU$759
28 Sept - 29 Sept
includes taxes & fees
This vacation home is within the region of Portobelo National Park and Isla Mamey.
Opens in a new windowCaribbean Paradise - Beachfront Getaway
Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

Portobelo
The price is AU$687 per night from 28 Sept to 29 Sept
AU$687
28 Sept - 29 Sept
includes taxes & fees
With a stay at this vacation home in Portobelo, you'll be just steps from Real Aduana de Portobelo and Fuerte San Jerónimo.
Opens in a new windowCasa Dinis - Loft - CON Vistas Bahia DE Portobelo
Nice house in Portobelo, Skybluebyguanche

Nice house in Portobelo, Skybluebyguanche

Portobelo
When you stay at this vacation home in Mechi, you'll be near the beach and within a 5-minute drive of Portobelo National Park.
Opens in a new windowNice house in Portobelo, Skybluebyguanche
Cara al mar Cacique

Cara al mar Cacique

Cacique
This beach vacation home is 1.3 mi (2.2 km) from Blanca Beach and 1.4 mi (2.2 km) from Isla Mamey.
Opens in a new windowCara al mar Cacique
Casa Frente al Mar - Isla Grande

Casa Frente al Mar - Isla Grande

Provincia de Colón
This vacation home is 5.3 mi (8.5 km) from Isla Mamey and 8 mi (12.9 km) from Blanca Beach.
Opens in a new windowCasa Frente al Mar - Isla Grande
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isla Grande Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Isla Grande vacation homes are the perfect way for you to wing it.

Holiday houses in Isla Grande let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Isla Grande in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Isla Grande adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Isla Grande with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Isla Grande vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Isla Grande Holiday Homes essential information

Accommodation
26 Holiday Homes
Lowest Price
AU$139
Highest Price
AU$919
Popular accommodation
Spacious Beach House on the ocean front with huge pool and patio., Cabaña La Punta op het Strand!!, Casa Dinis - Casa Grande - Centro DE Portobelo, A fantastic place between the sea and the jungle, Caribbean Paradise - Beachfront Getaway, Casa Dinis - Loft - CON Vistas Bahia DE Portobelo, Nice house in Portobelo, Skybluebyguanche , Cara al mar Cacique, Casa Frente al Mar - Isla Grande

Top trending hotels in Isla Grande

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande, Isla Grande, Colon
With a stay at Ordovician Beach Resort in Isla Grande, you'll be in a national park and close to Isla Mamey.
Opens in a new windowOrdovician Beach Resort
Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira, Isla Grande, Provincia de Colón
Fully refundableReserve now, pay when you stay
The price is AU$139 per night from 28 Sept to 29 Sept
AU$139
28 Sept - 29 Sept
includes taxes & fees
When you stay at Hotel Cocotal in Isla Grande, you'll be close to Isla Mamey.
Opens in a new windowHotel Cocotal
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01, Isla Grande, Colón Province
Fully refundableReserve now, pay when you stay
The price is AU$172 per night from 28 Sept to 29 Sept
AU$172
28 Sept - 29 Sept
includes taxes & fees
With a stay at HOTEL ISLA GRANDE in Isla Grande, you'll be on the beach and close to Isla Mamey.
Opens in a new windowHOTEL ISLA GRANDE
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Brother Sun Villas

Brother Sun Villas

3 out of 5
Camino Al Faro, Isla Grande
When you stay at Brother Sun Villas in Isla Grande, you'll be on the beach and 13 minutes by car from Isla Mamey.
Opens in a new windowBrother Sun Villas
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.