Book Holiday Homes in Isla Grande

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Featured Holiday Homes in Isla Grande

Spacious Beach House on the ocean front with huge pool and patio.

Spacious Beach House on the ocean front with huge pool and patio.

Republic de Panama - Guanche - Colon - P Colon
Located in Mechi, this vacation home is by the ocean, a 4-minute drive from Playa La Angosta and 8 minutes from Portobelo National Park.
Opens in a new windowSpacious Beach House on the ocean front with huge pool and patio.
Cabaña La Punta op het Strand!!

Cabaña La Punta op het Strand!!

Colón Province
The price is AU$262 per night from 22 Dec to 23 Dec
AU$262
22 Dec - 23 Dec
includes taxes & fees
This vacation home is within the vicinity of Isla Mamey and Portobelo National Park.
Opens in a new windowCabaña La Punta op het Strand!!
Casa Frente al Mar - Isla Grande

Casa Frente al Mar - Isla Grande

Provincia de Colón Provincia de Colón
This vacation home is 5.3 mi (8.5 km) from Isla Mamey and 8 mi (12.9 km) from Blanca Beach.
Opens in a new windowCasa Frente al Mar - Isla Grande
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Nice house in Portobelo, Skybluebyguanche

Nice house in Portobelo, Skybluebyguanche

Portobelo Colón Province
When you stay at this vacation home in Mechi, you'll be near the beach and within a 5-minute drive of Portobelo National Park.
Opens in a new windowNice house in Portobelo, Skybluebyguanche
Cara al mar Cacique

Cara al mar Cacique

Cacique Colón Province
This beach vacation home is 1.3 mi (2.2 km) from Blanca Beach and 1.4 mi (2.2 km) from Isla Mamey.
Opens in a new windowCara al mar Cacique
A fantastic place between the sea and the jungle

A fantastic place between the sea and the jungle

Colon Colón Province
This beach vacation home is 6.9 mi (11.1 km) from Isla Mamey and 9.6 mi (15.4 km) from Blanca Beach.
Opens in a new windowA fantastic place between the sea and the jungle
Casa Anzuelo is an oceanfront home that is all about the water and nature.

Casa Anzuelo is an oceanfront home that is all about the water and nature.

Portobelo Colon
This vacation home is 0.1 mi (0.1 km) from Blanca Beach and 2.7 mi (4.4 km) from Isla Mamey.
Opens in a new windowCasa Anzuelo is an oceanfront home that is all about the water and nature.
Despierta sobre el mar

Despierta sobre el mar

2 out of 5
Garrote Colón Province
The price is AU$166 per night from 23 Dec to 24 Dec
AU$166
23 Dec - 24 Dec
includes taxes & fees
With a stay at this vacation home in Puerto Lindo, you'll be within a 15-minute drive of Isla Mamey and Portobelo National Park.
Opens in a new windowDespierta sobre el mar
4-bedroom beachfront paradise in Palenque with AC, pool, walking trail and more!

4-bedroom beachfront paradise in Palenque with AC, pool, walking trail and more!

Palenque Colon
With a stay at this vacation home in Palenque, you'll be 14.9 mi (24 km) from Portobelo National Park and 23 mi (37 km) from Isla Mamey.
Opens in a new window4-bedroom beachfront paradise in Palenque with AC, pool, walking trail and more!
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isla Grande Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Isla Grande vacation homes are the perfect way for you to wing it.

Holiday houses in Isla Grande let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Isla Grande in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Isla Grande adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Isla Grande with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Isla Grande vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Isla Grande Holiday Homes essential information

Accommodation
19 Holiday Homes
Lowest Price
AU$134
Highest Price
AU$594
Popular accommodation
Spacious Beach House on the ocean front with huge pool and patio., Cabaña La Punta op het Strand!!, Casa Frente al Mar - Isla Grande, Nice house in Portobelo, Skybluebyguanche , Cara al mar Cacique, A fantastic place between the sea and the jungle, Casa Anzuelo is an oceanfront home that is all about the water and nature., Despierta sobre el mar , 4-bedroom beachfront paradise in Palenque with AC, pool, walking trail and more!

Top trending hotels in Isla Grande

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande Isla Grande Colon
With a stay at Ordovician Beach Resort in Isla Grande, you'll be in a national park and close to Isla Mamey.
Opens in a new windowOrdovician Beach Resort
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
Fully refundableReserve now, pay when you stay
The price is AU$156 per night from 22 Dec to 23 Dec
AU$156
22 Dec - 23 Dec
includes taxes & fees
With a stay at HOTEL ISLA GRANDE in Isla Grande, you'll be on the beach and close to Isla Mamey.
Opens in a new windowHOTEL ISLA GRANDE
Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira Isla Grande Provincia de Colón
The price is AU$134 per night from 22 Dec to 23 Dec
AU$134
22 Dec - 23 Dec
includes taxes & fees
When you stay at Hotel Cocotal in Isla Grande, you'll be close to Isla Mamey.
Opens in a new windowHotel Cocotal
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Deluxe Beachfront 4-bedroom house in Colón Province

Deluxe Beachfront 4-bedroom house in Colón Province

Colón Province Colón Province
The price is AU$594 per night from 22 Dec to 23 Dec
AU$594
22 Dec - 23 Dec
includes taxes & fees
When you stay at this vacation home in Isla Grande, you'll be close to Isla Mamey.
Opens in a new windowDeluxe Beachfront 4-bedroom house in Colón Province
Don't see what you're looking for?
See all available properties in Isla Grande
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.