Book Holiday Homes in Des Moines
More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)
We keep it easy with the option to pay now or later on select accommodation
Book up 'til the last second - millions of rooms to crash tonight^
Featured Holiday Homes in Des Moines
SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!
Des Moines IA
The price is AU$775 per night from 20 Jan to 21 Jan
AU$775
20 Jan - 21 Jan 2026
includes taxes & fees
With a stay at this vacation home in Des Moines (Woodland Heights), you'll be within a 15-minute drive of Casey's Center and Iowa State Fairgrounds.
AMAZING & A PARTY BARN… HOT TUB, PL TBl, PNG PNG, & ARCADE! ACCESS TO POOLS!
West Des Moines IA
The price is AU$1,107 per night from 30 Dec to 31 Dec
AU$1,107
30 Dec - 31 Dec
includes taxes & fees
With a stay at this vacation home in West Des Moines, you'll be within a 15-minute drive of Jordan Creek Town Center and Casey's Center.
Downtown Skyline Views in Modern Townhome with Rooftop Patios
Des Moines IA
With a stay at this vacation home, you'll be centrally located in Des Moines, a 3-minute drive from Casey's Center and 10 minutes from Iowa State ...
Save an average of 15% on thousands of hotels when you're signed in
Entire Bungalow with Fenced-In Yard in Trendy Neighborhood, Central Des Moines
Des Moines IA
The price is AU$350 per night from 20 Jan to 21 Jan
AU$350
20 Jan - 21 Jan 2026
includes taxes & fees
With a stay at this vacation home in Des Moines, you'll be within a 15-minute drive of Casey's Center and Iowa State Fairgrounds.
The Vintage Haven. A cozy home 5 mins from Downtown Des Moines. Pet-Friendly
Des Moines IA
The price is AU$537 per night from 20 Jan to 21 Jan
AU$537
20 Jan - 21 Jan 2026
includes taxes & fees
With a stay at this vacation home in Des Moines, you'll be a 4-minute drive from Casey's Center and 9 minutes from Iowa State Fairgrounds.
Charming 4 Bedroom Home With Beautiful Backyard
Des Moines IA
With a stay at this vacation home in Des Moines (North of Grand), you'll be within a 15-minute drive of Casey's Center and Jordan Creek Town Center.
Hot Tub, Fenced Yard, Games, Office/Gym + Pets Ok!
Des Moines IA
The price is AU$711 per night from 1 Jan to 2 Jan
AU$711
1 Jan - 2 Jan 2026
includes taxes & fees
With a stay at this vacation home in Des Moines (Drake), you'll be within a 15-minute drive of Casey's Center and Jordan Creek Town Center.
Newly Remodeled Brick Home with wall Sculptures by the Airport
Des Moines IA
The price is AU$359 per night from 20 Jan to 21 Jan
AU$359
20 Jan - 21 Jan 2026
includes taxes & fees
With a stay at this vacation home in Des Moines (Southwestern Hills), you'll be within a 15-minute drive of Casey's Center and Iowa State Fairgrounds.
LUXURY GETAWAY! ARCADE, POOL TBL, PING PONG, HOT TUB, DECK! ACCESS TO POOLS!
Waukee IA
The price is AU$781 per night from 20 Jan to 21 Jan
AU$781
20 Jan - 21 Jan 2026
includes taxes & fees
With a stay at this vacation home in Waukee, you'll be next to a golf course, within a 10-minute drive of Jordan Creek Town Center and Hawthorne Plaza.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Des Moines Holiday Houses
Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Des Moines vacation homes are the perfect way for you to wing it.
Holiday houses in Des Moines let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Des Moines in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Des Moines adventures, obvs.
If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Des Moines with your name on it.
No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Des Moines vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.
Des Moines Holiday Homes essential information
Accommodation | 221 Holiday Homes |
|---|---|
Lowest Price | AU$140 |
Highest Price | AU$1,107 |
Popular accommodation | SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!, AMAZING & A PARTY BARN… HOT TUB, PL TBl, PNG PNG, & ARCADE! ACCESS TO POOLS!, Downtown Skyline Views in Modern Townhome with Rooftop Patios, Entire Bungalow with Fenced-In Yard in Trendy Neighborhood, Central Des Moines, The Vintage Haven. A cozy home 5 mins from Downtown Des Moines. Pet-Friendly, Charming 4 Bedroom Home With Beautiful Backyard, Hot Tub, Fenced Yard, Games, Office/Gym + Pets Ok!, Newly Remodeled Brick Home with wall Sculptures by the Airport, LUXURY GETAWAY! ARCADE, POOL TBL, PING PONG, HOT TUB, DECK! ACCESS TO POOLS! |
Top trending hotels in Des Moines
Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
The price is AU$140 per night from 1 Jan to 2 Jan
AU$140
1 Jan - 2 Jan 2026
includes taxes & fees
When you stay at Fairfield Inn and Suites by Marriott Des Moines West in West Des Moines, you'll be in the business district, within a 15-minute drive of Jordan ...
Stoney Creek Hotel Des Moines - Johnston
5291 Stoney Creek Court Johnston IA
Fully refundableReserve now, pay when you stay
The price is AU$165 per night from 20 Jan to 21 Jan
AU$165
20 Jan - 21 Jan 2026
includes taxes & fees
Located in Johnston, Stoney Creek Hotel Des Moines - Johnston is in the suburbs, within a 15-minute drive of Jordan Creek Town Center and Drake University.
Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
The price is AU$242 per night from 4 Jan to 5 Jan
AU$242
4 Jan - 5 Jan 2026
includes taxes & fees
With a stay at Hotel Fort Des Moines, Curio Collection by Hilton, you'll be centrally located in Des Moines, a 2-minute drive from Casey's Center and 10 minutes ...
Save an average of 15% on thousands of hotels when you're signed in
Home2 Suites by Hilton Des Moines at Drake University
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
The price is AU$151 per night from 21 Dec to 22 Dec
AU$151
21 Dec - 22 Dec
includes taxes & fees
With a stay at Home2 Suites by Hilton Des Moines at Drake University in Des Moines (Drake), you'll be steps from Drake University and a 4-minute drive from Iowa ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More ways to explore Des Moines
**Terms and Conditions apply.
^Subject to availability and chosen travel dates.