Book Holiday Homes in Cape Girardeau

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Featured Holiday Homes in Cape Girardeau

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau
The price is AU$387 per night from 15 May to 16 May
AU$387
includes taxes & fees
15 May - 16 May
When you stay at this vacation home in Cape Girardeau, you'll be on a river, just steps from Shawnee National Forest and Mississippi River.
Serenity South -- Gardens, River-Views, and Refreshing Space
Notting Hill Cottage

Notting Hill Cottage

Alto Pass
With a stay at this vacation home in Alto Pass, you'll be a 1-minute drive from Shawnee National Forest and 6 minutes from Peachbarn Winery.
Notting Hill Cottage
Beautiful location in the secluded woods

Beautiful location in the secluded woods

Pomona
The price is AU$299 per night from 15 May to 16 May
AU$299
includes taxes & fees
15 May - 16 May
When you stay at this vacation home in Pomona, you'll be 1 minutes by foot from Shawnee National Forest.
Beautiful location in the secluded woods
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* On the Wine Trail * Hot Tub * Wi-Fi *

* On the Wine Trail * Hot Tub * Wi-Fi *

Alto Pass
With a stay at this vacation home, you'll be centrally located in Alto Pass, steps from Shawnee National Forest and 15 minutes by foot from Peachbarn ...
* On the Wine Trail * Hot Tub * Wi-Fi *
Wine Trail, Cozy Cabin plus hot tub

Wine Trail, Cozy Cabin plus hot tub

Cobden
With a stay at this vacation home in Cobden, you'll be within a 10-minute drive of Shawnee National Forest and Owl Creek Vineyard.
Wine Trail, Cozy Cabin plus hot tub
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *

* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *

Alto Pass
The price is AU$413 per night from 3 May to 4 May
AU$413
includes taxes & fees
3 May - 4 May
With a stay at this vacation home, you'll be centrally located in Alto Pass, steps from Shawnee National Forest and 15 minutes by foot from Peachbarn ...
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural

Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural

Cobden
Located in Cobden, this vacation home is in a rural location, a 1-minute drive from Shawnee National Forest and 9 minutes from StarView Vineyards.
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Cape Girardeau
The price is AU$467 per night from 5 May to 6 May
AU$467
includes taxes & fees
5 May - 6 May
Located in Cape Girardeau, this vacation home is in a rural location, within a 5-minute drive of Twin Trees Park and Shawnee National Forest.
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Cape Girardeau
The price is AU$847 per night from 18 May to 19 May
AU$847
includes taxes & fees
18 May - 19 May
With a stay at this vacation home in Cape Girardeau, you'll be within a 5-minute drive of Shawnee National Forest and Mississippi River.
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cape Girardeau Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Cape Girardeau vacation homes are the perfect way for you to wing it.

Holiday houses in Cape Girardeau let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Cape Girardeau in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Cape Girardeau adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Cape Girardeau with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Cape Girardeau vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Cape Girardeau Holiday Homes essential information

Accommodation
53 Holiday Homes
Lowest Price
AU$127
Highest Price
AU$847
Popular accommodation
Serenity South -- Gardens, River-Views, and Refreshing Space, Notting Hill Cottage, Beautiful location in the secluded woods , * On the Wine Trail * Hot Tub * Wi-Fi *, Wine Trail, Cozy Cabin plus hot tub, * Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *, Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural, 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool, 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Top trending hotels in Cape Girardeau

The Riverview

The Riverview

3.5 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$189 per night from 11 May to 12 May
AU$189
includes taxes & fees
11 May - 12 May
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Shawnee National Forest and Mississippi ...
The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$159 per night from 6 May to 7 May
AU$159
includes taxes & fees
6 May - 7 May
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive ...
Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street, Cape Girardeau, MO
Fully refundable
The price is AU$175 per night from 1 Jun to 2 Jun
AU$175
includes taxes & fees
1 June - 2 June
When you stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Shawnee ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Save an average of 15% on thousands of hotels when you're signed in
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$127 per night from 11 May to 12 May
AU$127
includes taxes & fees
11 May - 12 May
Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, within a 5-minute drive of Saint Francis Medical Center and Saint Francis ...
Pear Tree Inn Cape Girardeau West
Don't see what you're looking for?
See all available properties in Cape Girardeau
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.