Book Northwest San Antonio hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Northwest San Antonio

Cheap Northwest San Antonio hotels

Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center

2.5 out of 5
11426 IH 10 W, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$160 per night from 13 Jun to 14 Jun
AU$160
per night
13 Jun - 14 Jun
When you stay at Hampton Inn & Suites San Antonio Northwest/Medical Center in San Antonio, you'll be in the business district, within a 5-minute drive of USAA ...
Hampton Inn & Suites San Antonio Northwest/Medical Center
La Cantera Resort & Spa

La Cantera Resort & Spa

4 out of 5
16641 La Cantera Pkwy, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$710 per night from 18 Jun to 19 Jun
AU$710
per night
18 Jun - 19 Jun
When you stay at La Cantera Resort & Spa in San Antonio, you'll be in a shopping district, within a 5-minute drive of The Shops of La Cantera and University ...
La Cantera Resort & Spa
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

2.5 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$158 per night from 10 Jun to 11 Jun
AU$158
per night
10 Jun - 11 Jun
With a stay at La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW in San Antonio (Medical Center District), you'll be a 4-minute drive from University ...
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Save an average of 15% on thousands of hotels when you're signed in
The Westin San Antonio North

The Westin San Antonio North

4 out of 5
9821 Colonnade Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$204 per night from 9 Jun to 10 Jun
AU$204
per night
9 Jun - 10 Jun
Located in San Antonio (Vance Jackson), The Westin San Antonio North is within a 15-minute drive of The Shops of La Cantera and Six Flags Fiesta Texas.
The Westin San Antonio North
Comfort Inn and Suites Near Medical Center

Comfort Inn and Suites Near Medical Center

2.5 out of 5
6039 IH 10 West, Exit #565B-Vance Jackson Rd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$110 per night from 4 Jun to 5 Jun
AU$110
per night
4 Jun - 5 Jun
When you stay at Comfort Inn and Suites Near Medical Center in San Antonio, you'll be near the airport, within a 10-minute drive of San Antonio Zoo and Aquarium ...
Comfort Inn and Suites Near Medical Center
Clarion Pointe near Medical Center

Clarion Pointe near Medical Center

2.5 out of 5
4803 Manitou, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$98 per night from 5 Jun to 6 Jun
AU$98
per night
5 Jun - 6 Jun
With a stay at Clarion Pointe near Medical Center in San Antonio, you'll be within a 10-minute drive of North Star Mall and USAA Corporate Office ...
Clarion Pointe near Medical Center
Spark By Hilton San Antonio Northwest near Six Flags

Spark By Hilton San Antonio Northwest near Six Flags

3 out of 5
6755 North Loop 1604 West, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$149 per night from 9 Jun to 10 Jun
AU$149
per night
9 Jun - 10 Jun
With a stay at Spark By Hilton San Antonio Northwest near Six Flags, you'll be centrally located in San Antonio, just a 4-minute walk from University of Texas ...
Spark By Hilton San Antonio Northwest near Six Flags
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3 out of 5
8318 I-10 West, San Antonio, TX
Fully refundable
The price is AU$125 per night from 9 Jun to 10 Jun
AU$125
per night
9 Jun - 10 Jun
With a stay at Country Inn & Suites by Radisson, San Antonio Medical Center, TX in San Antonio (Medical Center District), you'll be a 4-minute drive from University ...
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$160 per night from 2 Jun to 3 Jun
AU$160
per night
2 Jun - 3 Jun
With a stay at Drury Inn & Suites San Antonio Northwest Medical Center in San Antonio, you'll be a 4-minute drive from USAA Corporate Office Headquarters and ...
Drury Inn & Suites San Antonio Northwest Medical Center
Don't see what you're looking for?
See all available properties in Northwest San Antonio
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.

Northwest San Antonio hotels essential information

Accommodation
578 hotels
Lowest Price
AU$98
Highest Price
AU$710
Popular hotels
Hampton Inn & Suites San Antonio Northwest/Medical Center, La Cantera Resort & Spa, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW, The Westin San Antonio North, Comfort Inn and Suites Near Medical Center, Clarion Pointe near Medical Center, Spark By Hilton San Antonio Northwest near Six Flags, Country Inn & Suites by Radisson, San Antonio Medical Center, TX, Drury Inn & Suites San Antonio Northwest Medical Center

Most recent Northwest San Antonio hotel reviews

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.