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Top trending hotels in Downtown San Francisco

Holiday Inn Golden Gateway, an IHG Hotel

Holiday Inn Golden Gateway, an IHG Hotel

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
Fully refundable
The price is AU$238 per night from 28 May to 29 May
AU$238
per night
28 May - 29 May
In the heart of San Francisco, Holiday Inn Golden Gateway, an IHG Hotel is within a 5-minute drive of Lombard Street and Kaiser Permanente Medical Center.
Holiday Inn Golden Gateway, an IHG Hotel
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
The price is AU$354 per night from 10 May to 11 May
AU$354
per night
10 May - 11 May
With a stay at Hyatt Regency San Francisco in San Francisco (Downtown San Francisco), you'll be a 5-minute walk from Embarcadero Center and 11 minutes by foot ...
Hyatt Regency San Francisco
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is AU$200 per night from 10 May to 11 May
AU$200
per night
10 May - 11 May
With a stay at Club Quarters Hotel in San Francisco, you'll be centrally located in San Francisco, a 4-minute walk from TransAmerica Pyramid and a 3-minute drive ...
Club Quarters Hotel in San Francisco
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King George Hotel

King George Hotel

3 out of 5
334 Mason Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is AU$158 per night from 22 May to 23 May
AU$158
per night
22 May - 23 May
With a stay at King George Hotel, you'll be centrally located in San Francisco, steps from Union Square and 14 minutes by foot from Moscone Convention ...
King George Hotel
The Marker San Francisco

The Marker San Francisco

4 out of 5
501 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is AU$193 per night from 10 May to 11 May
AU$193
per night
10 May - 11 May
A stay at The Marker San Francisco places you in the heart of San Francisco, within a 5-minute drive of Moscone Convention Center and Lombard Street.
The Marker San Francisco
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is AU$237 per night from 10 May to 11 May
AU$237
per night
10 May - 11 May
With a stay at Chancellor Hotel on Union Square, you'll be centrally located in San Francisco, a 5-minute walk from Dragon's Gate and 11 minutes by foot from ...
Chancellor Hotel on Union Square
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

4.5 out of 5
335 Powell Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is AU$279 per night from 27 May to 28 May
AU$279
per night
27 May - 28 May
With a stay at The Westin St. Francis San Francisco on Union Square, you'll be centrally located in San Francisco, steps from Union Square and 13 minutes by ...
The Westin St. Francis San Francisco on Union Square
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is AU$245 per night from 20 May to 21 May
AU$245
per night
20 May - 21 May
With a stay at Handlery Union Square Hotel, you'll be centrally located in San Francisco, steps from Union Square and 14 minutes by foot from Moscone Convention ...
Handlery Union Square Hotel
Hotel Stratford

Hotel Stratford

2 out of 5
242 Powell St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is AU$195 per night from 10 May to 11 May
AU$195
per night
10 May - 11 May
In the heart of San Francisco, Hotel Stratford is within a 5-minute drive of Moscone Convention Center and Lombard Street.
Hotel Stratford
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Downtown San Francisco Hotels

Haven’t you been dying to check out that swanky new coffee shop? What about the recently opened bar serving drinks in mason jars? And let’s not forget about the barber shops willing to give you a shaved-on-the-sides, long-on-top cut whenever you want. Don’t worry; we’ll help you find the best deals at hotels in Downtown San Francisco.

This hip new ’hood will charm the-you-know-what off you. Downtown San Francisco hotels are comfortable and affordable, and many offer amenities like room service for those late-night meals, as well as a pool to swim in. Some of these hotels will also have you near great shopping such as souvenir shops, clothing boutiques and everything in between. Don’t feel like leaving the hotel for dinner and drinks? Hang out in the lobby bar and meet some of your fellow travellers—you never what kinds of stories they have in their memory log.

There’s no point in going somewhere if you’re not going to stay where all the action is. lastminute.com.au gets you the best offers on where to stay in Downtown San Francisco so you don’t have to waste endless hours searching online. The trip of a lifetime is at your fingertips. Click and go!

Downtown San Francisco hotels essential information

Accommodation
906 hotels
Lowest Price
AU$158
Highest Price
AU$354
Popular hotels
Holiday Inn Golden Gateway, an IHG Hotel, Hyatt Regency San Francisco, Club Quarters Hotel in San Francisco, King George Hotel, The Marker San Francisco, Chancellor Hotel on Union Square, The Westin St. Francis San Francisco on Union Square, Handlery Union Square Hotel, Hotel Stratford

Most recent Downtown San Francisco hotel reviews